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MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
TranscriptomicsTranscriptional responses of Acinetobacter baumannii ATCC 17978 to limiting iron availability
A. baumannii ATCC 17978 cells were incubated under iron replete (mueller-hinton) and iron limiting (MH + 200 µM 2,2'-dipyridyl) conditions, total RNA was extracted when cultures reached OD600=0.7. The probes on the microarray cover all predicted open reading frames (at least 4 per ORF) and addition...
ORGANISM(S): Acinetobacter baumannii 
2013-10-18 | E-GEOD-24921 | biostudies-arrayexpress
TranscriptomicsComparative transcriptional analysis of Acinetobacter baumannii strain ATCC 17978 and strain 17978hm
In this study the transcriptomes of Acinetobacter baumannii strains ATCC 17978 and 17978hm were compared. Strain 17978hm is a hns knockout derivative of strain ATCC 17978. Strain 17978hm displays a hyper-motile phenotype on semi-solid Mueller-Hinton (MH) media (0.25% agar). ATCC 17978 and 17978hm fr...
ORGANISM(S): Acinetobacter baumannii 
2013-08-05 | E-GEOD-40681 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of chlorhexidine shock in Acinetobacter baumannii
In this study the transcriptomic changes occurring in A. baumannii ATCC 17978 in response to shock treament using the biocide chlorhexdine were determined. A. baumannii ATCC 17978 cells were grown at 37°C with shaking (200rpm) in 35mL cultures in MH broth to OD600=0.75, at which time they were spli...
ORGANISM(S): Acinetobacter baumannii 
2013-12-03 | E-GEOD-51525 | biostudies-arrayexpress
UnknownThe zinc efflux activator SczA protects Streptococcus pneumoniae serotype 2 D39 from intracellular zinc toxicity.
Not available
S-EPMC5426980 | biostudies-literature
TranscriptomicsRNA sequencing of ATCC 17978hm Acineotbacter baumannii strain and CpdA mutant
Difference in RNA expression levels between Acinetobacter baumannii cells expressing high and low levels of cyclic AMP Total RNA obtained from Acineotbacter baumannii bacterial cells in Log phase gown in MH broth culture, isolated RNA in triplicate from three expreiment. cpdA::Tn mutant and 17978hm ...
ORGANISM(S): Acinetobacter baumannii 
2015-06-21 | E-GEOD-64935 | biostudies-arrayexpress
UnknownDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.
Not available
S-EPMC9084593 | biostudies-literature
ProteomicsProteomic analysis Enterococcus faecium
Proteomic analysis Enterococcus faecium samples to assess proteomic alterations (20220922_NSco_Stinear)
ORGANISM(S): Enterococcus faecalis (Streptococcus faecalis) 
2024-08-15 | PXD039831 | Pride
Enterococcus faecium 
ProteomicsEnterococcus faecium mutant proteome analysis
DIA based comparsion of padR mutant, complement and WT strains
ORGANISM(S): Enterococcus faecalis (Streptococcus faecalis) 
2024-08-15 | PXD039832 | Pride
Enterococcus faecium 
UnknownDysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae.
Not available
S-EPMC4366526 | biostudies-literature
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