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Proteomics,MultiomicsTranscriptional and translational regulatory responses to iron limitation in the globally distributed marine bacterium Candidatus Pelagibacter ubique
Investigation of the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation in natural seawater media supplemented with a siderophore to chelate iron. Quantitative peptide mass spectrometry revealed that sfuC protein abundance increased 27-fold, despite an average de...
ORGANISM(S): Candidatus Pelagibacter Ubique (ncbitaxon:198252) 
2020-05-18 | MSV000085445 | MassIVE
TranscriptomicsM. sedula transcriptional response to ferrous iron and RISC supplements
Abstract: The crenarchaeal order Sulfolobales collectively contains at least five major terminal oxidase complexes. Based on genome sequence information, all five complexes are found only in Metallosphaera sedula and Sulfolobus tokodaii, the two sequenced Sulfolobales capable of iron oxidization. Wh...
ORGANISM(S): Metallosphaera sedula 
2008-10-22 | E-GEOD-12044 | biostudies-arrayexpress
TranscriptomicsTranscriptional Response to Iron Limitation in Pelagibacter ubique
We investigated the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation. Differential expression was observed for genes in iron acquisition and incorporation operons. SfuC in particular was 16 times higher in iron-limited cultures and encodes a periplasmic iron-bi...
ORGANISM(S): Candidatus Pelagibacter ubique HTCC1062 
2010-05-05 | E-GEOD-20962 | biostudies-arrayexpress
TranscriptomicsMR-1 gene expression profiles of iron response
Time-series transcriptional profiles of Shewanella oneidensis type strain MR-1 under iron depletion and repletion conditions. Iron homeostasis of Shewanella oneidensis, a gamma-proteobacterium possessing high iron content, is regulated by a global transcription factor Fur. However, knowledge is inco...
ORGANISM(S): Shewanella oneidensis MR-1 
2010-01-12 | E-GEOD-15334 | biostudies-arrayexpress
TranscriptomicsResponse of Henle 407 cells during Toxoplasma gondii infection
The innate immune response of mucosal epithelial cells during pathogen invasion plays a central role in immune regulation in the gut. Toxoplasma gondii (T. gondii) is a protozoan intracellular parasite that is usually transmitted through oral infection. Although much of the information on immunity...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-18085 | biostudies-arrayexpress
UnknownEffect of aspirin on deaths associated with sepsis in healthy older people (ANTISEPSIS): a randomised, double-blind, placebo-controlled primary prevention trial.
Not available
S-EPMC7957956 | biostudies-literature
TranscriptomicsUntreated and iron-treated ARPE-19 cell gene expression
To characterize the potential molecular pathway(s) affected by iron treatment and identify the one(s) responsible for C3 induction, we performed a whole genome microarray on untreated ARPE-19 cells and cells treated with 250 ?M FAC for 48h/2d. Gene expression was compared between untreated and FAC-t...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-67603 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in testis of pigs with extreme high and low levels of androstenone.
Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis. Here we use microarrays to study the expression of thousands of genes simultaneously in testis of high and low a...
ORGANISM(S): Sus scrofa 
2007-11-26 | E-GEOD-7409 | biostudies-arrayexpress
TranscriptomicsUsing transient nondisjunction to generate disomic strains of yeast
Background. Most methods for constructing aneuploid yeast strains that have gained a specific chromosome rely on spontaneous failures of cell division fidelity. In Saccharomyces cerevisiae, extra chromosomes can be obtained when errors in meiosis or mitosis lead to nondisjunction, or when nuclear br...
ORGANISM(S): Saccharomyces cerevisiae 
2009-01-13 | E-GEOD-14377 | biostudies-arrayexpress
TranscriptomicsTranscriptional dysregulation mediated by ROS in normal human haematopoietic progenitor cells expressing mutant N-RASG12D
The current study investigated the effect of RAS-induced ROS production on gene expression in normal human haematopoietic progenitor cells (HPC) using gene expression profiling (GEP) and assessed whether ROS-induced gene expression changes contributed to the pro-proliferative phenotype. In order to...
ORGANISM(S): Homo sapiens 
2015-11-30 | E-MTAB-3551 | biostudies-arrayexpress
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