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UnknownOptimization of the BLASTN substitution matrix for prediction of non-specific DNA microarray hybridization.
Not available
S-EPMC2831327 | biostudies-literature
TranscriptomicsYeast background with high-concentration spikes
Microarray measurements are susceptible to error caused by cross-hybridization and bulk hybridization. To characterize the effect of these off-target interactions, we analyzed samples made from baseline (S. cerevisiae) alone or mixed with a high-concentration 1kb spike. The spike is a 1 kb sequence ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-03-21 | E-GEOD-16980 | biostudies-arrayexpress
TranscriptomicsTumor expression data from neoadjuvant trial of cisplatin monotherapy in triple negative breast cancer patients
Evidence suggests that BRCA1 mutation associated tumors have increased sensitivity to DNA damaging agents like cisplatin. Sporadic triple negative breast cancers (TNBC) have many phenotypic similarities to BRCA1 tumors and may have a similar sensitivity to cisplatin. We tested the efficacy of cisp...
ORGANISM(S): Homo sapiens 
2009-11-04 | E-GEOD-18864 | biostudies-arrayexpress
MetabolomicsAn online atlas of human plasma metabolite signatures of gut microbiome composition

Human gut microbiota produce a variety of molecules, some of which enter the bloodstream and impact health. Conversely, dietary or pharmacological compounds may affect the microbiota before entering the circulation. Characterization of these interactions is an important step towards understanding...

2022-05-19 | MTBLS407 | MetaboLights
UnknownTumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen.
Not available
S-EPMC4590711 | biostudies-literature
TranscriptomicsPredicting the efficacy of anthracyclines in breast cancer (BC) patients: The results of the TOP trial
PURPOSE: Validated biomarkers predictive of response/resistance to anthracyclines in breast cancer are currently lacking. The neoadjuvant TOP trial, in which patients with estrogen receptor (ER)-negative tumors were treated with anthracycline (epirubicin) monotherapy, was specifically designed to ev...
ORGANISM(S): Homo sapiens 
2010-01-26 | E-GEOD-16446 | biostudies-arrayexpress
UnknownImpact of a multimedia website with patient experiences of multiple sclerosis (PExMS) on immunotherapy decision-making: study protocol for a pilot randomised controlled trial in a mixed-methods design.
Not available
S-EPMC7788927 | biostudies-literature
UnknownMinimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status.
Not available
S-EPMC2995741 | biostudies-literature
UnknownNeoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy.
Not available
S-EPMC10076713 | biostudies-literature
UnknownCoagulation abnormalities and vascular complications are common in PGM1-CDG.
Not available
S-EPMC12682075 | biostudies-literature
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