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TranscriptomicsIL-4-primed bone marrow macrophages isolated from C57Bl6/J or Balb/cAnNCrl mice
To compare the expression profile of differentiated mouse bone marrow macrophages (BMM) in response to IL-4, we have employed whole genome microarray expression profiling. For this purpose, bone marrow cells were isolated from 8 to 12 weeks old C57BL6/J and Balb/cAnNCrl mice and cultured in the pres...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-14644 | biostudies-arrayexpress
TranscriptomicsAnalysis of TLR4 induced transcriptional responses in interleukin 4 primed mouse macrophages
Interferon (IFN)γ and interleukin (IL)-4 are central regulators of T helper 1 (Th1) and T helper 2 (Th2) immune responses, respectively. Both cytokines have a major impact on macrophage phenotypes: IFNγ–priming and subsequent TLR4 activation induces so called classically activated macrophages that a...
ORGANISM(S): Mus musculus 
2010-10-01 | E-GEOD-21895 | biostudies-arrayexpress
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