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GenomicsOral Epithelium Response of Electronic Cigarette Users to Electronic Cigarette
Oral Epithelium Response of Electronic Cigarette Users to Electronic Cigarette
PRJNA736429 | ENA
ProteomicsSmooth Muscle Cell Phenotypic Switch Induced by Cigarette Smoke Condensate
Cigarette smoke is a risk factor for inflammatory diseases, such as atherosclerosis. Tobacco smoke interacts with inflammatory cytokines to produce endothelial dysfunction and induces pro-inflammatory and pro-atherosclerotic effects in vascular tissue. Smooth muscle cells (SMCs) are present in the m...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD041174 | Pride
Atherosclerosis  cigarette smoke  electronic cigarette  phenotypic switch  smooth muscle cells 
TranscriptomicsA lower impact of exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment
In the context of tobacco harm-reduction strategy, the potential reduced impact of electronic cigarette (EC) exposure should be evaluated relative to the impact of cigarette smoke (CS) exposure. We conducted a series of in vitro studies to compare the biological impact of an acute exposure to aeroso...
ORGANISM(S): Homo sapiens 
2019-03-25 | E-MTAB-7577 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression of human periodontal ligament derived stem cell line exposed to 1 microMolar (uM) (-)-nicotine liquid or 1 uM nicotine electronic cigarette vapor extract against untreated control
Nicotine and cigarette smoking have been previously shown to inhibit the differentiation potential and miRNA expression of human periodontal ligament derived stem cells (PDLSCs). Electronic cigarette (EC) vapor also contains nicotine, as well as other non-nicotine compounds, and, like cigarette smok...
ORGANISM(S): Homo sapiens 
2019-09-30 | E-MTAB-7893 | biostudies-arrayexpress
ProteomicsCombined biological effects and lung proteomics analysis in mice reveal different toxic impacts of electronic cigarette aerosol and combustible cigarette smoke on the respiratory system
Combustible cigarettes produce many toxic substances that have been linked to diseases such as lung cancer and chronic obstructive pulmonary disease (COPD). Electronic cigarettes (e-cigarettes) can be used as an alternative to cigarettes for smokers who are unable or unwilling to quit. However, the ...
ORGANISM(S): Mus <genus> 
PXD035374 |
TranscriptomicsToxicity of the main electronic cigarette components, propylene glycol, glycerin and nicotine in Sprague Dawley rats in a 90-day OECD inhalation study complemented with molecular endpoints (RNE)
While the toxicity of the main constituents of electronic cigarette (ECIG) liquids, nicotine, propylene glycol (PG), and vegetable glycerin (VG), has been assessed individually in separate studies, limited data on the inhalation toxicity of them is available when in mixtures. In this 90-day subchron...
ORGANISM(S): Rattus norvegicus 
2017-11-03 | E-MTAB-5910 | biostudies-arrayexpress
TranscriptomicsMolecular impact of electronic cigarette aerosol exposure in human bronchial epithelium
Analysis of primary human bronchial epithelial cells grown in air liquid interface, exposed in vitro to whole tobacco cigarette smoke (48 puffs, 48 minutes) and electronic cigarette aerosol (400 puffs, 200 minutes). Electronic cigarette exposures included two flavors (menthol, tobacco) both with, an...
ORGANISM(S): Homo sapiens 
2016-10-12 | GSE82137 | GEO
TranscriptomicsToxicity of the main electronic cigarette components, propylene glycol, glycerin and nicotine in Sprague Dawley rats in a 90-day OECD inhalation study complemented with molecular endpoints (Lung)
The main constituents of electronic cigarette liquids are nicotine, propylene glycol (PG), and vegetable glycerin (VG), together with distilled water and flavors. To assess the toxicity of PG/VG mixtures with and without nicotine as basic components of liquids used in e-cigarettes, a 90-day rat inha...
ORGANISM(S): Rattus norvegicus 
2017-11-03 | E-MTAB-5545 | biostudies-arrayexpress
TranscriptomicsToxicity of Toxicity of the main electronic cigarette components, propylene glycol, glycerin and nicotine in Sprague Dawley rats in a 90-day OECD inhalation study complemented with molecular endpoints (Liver)
The main constituents of electronic cigarette liquids are nicotine, propylene glycol (PG), and vegetable glycerin (VG), together with distilled water and flavors. To assess the toxicity of PG/VG mixtures with and without nicotine as basic components of liquids used in e-cigarettes, a 90-day rat inha...
ORGANISM(S): Rattus norvegicus 
2017-11-03 | E-MTAB-5544 | biostudies-arrayexpress
GenomicsAbnormal expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users
Abnormal expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users
PRJNA1066343 | ENA
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