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TranscriptomicsRNA-Seq of control and ELL2-depleted MPC11 plasmacytoma cell lines
We report RNA-Seq data from MPC11 plasmacytoma cell lines transduced with either control hairpins (shGFP) or hairpins targeting the transcriptional elongation factor ELL2. ELL2 has been identified as regulating the alternative splicing and polyadenylation of immunoglobulin pre-mRNA, and is highly e...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40285 | biostudies-arrayexpress
GenomicsDetermining ELL2 direct targets via ChIPseq
Determining ELL2 direct targets via ChIPseq
PRJNA471339 | ENA
GenomicsThe multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue]
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue]
PRJNA436170 | ENA
GenomicsThe multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO]
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO]
PRJNA436147 | ENA
TranscriptomicsRNA-Seq of control and ELL2-depleted MPC11 plasmacytoma cell lines
We report RNA-Seq data from MPC11 plasmacytoma cell lines transduced with either control hairpins (shGFP) or hairpins targeting the transcriptional elongation factor ELL2. ELL2 has been identified as regulating the alternative splicing and polyadenylation of immunoglobulin pre-mRNA, and is highly ex...
ORGANISM(S): Mus musculus 
2012-09-07 | GSE40285 | GEO
UnknownConditional deletion of ELL2 induces murine prostate intraepithelial neoplasia.
Not available
S-EPMC5679084 | biostudies-literature
GenomicsDetermining ELL2 direct targets via ChIPseq
A plasma cell line was used to determine which genes have ELL2 protein bound to them.
ORGANISM(S): Mus musculus 
2018-05-15 | GSE114435 | GEO
TranscriptomicsThe multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue]
To understand the biological mechanism of ELL2 in multiple myeloma (MM), we show that the MM risk allele lowers ELL2 expression in CD138+ plasma cells (Pcombined=2.5×10-27; bcombined=-0.24 s.d.), but not in peripheral blood or other tissues. Consistent with this, several variants representing the MM...
ORGANISM(S): Homo sapiens 
2018-04-25 | GSE111210 | GEO
TranscriptomicsThe multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO]
To understand the biological mechanism of ELL2 in multiple myeloma (MM), we show that the MM risk allele lowers ELL2 expression in CD138+ plasma cells (Pcombined=2.5×10-27; bcombined=-0.24 s.d.), but not in peripheral blood or other tissues. Consistent with this, several variants representing the MM...
ORGANISM(S): Homo sapiens 
2018-04-25 | GSE111199 | GEO
UnknownELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells.
Not available
S-EPMC5761340 | biostudies-literature
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