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MetabolomicsEx-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...
2020-09-30 | MTBLS1495 | MetaboLights
MetabolomicsMetabolomic and Proteomic Stratification of Equine Osteoarthritis

Osteoarthritis (OA) is characterised by loss of articular cartilage, synovial membrane dysfunction and subchondral sclerosis. Few studies have used a global approach to stratify equine synovial fluid (SF) molecular profiles according to OA severity. SF was collected from 58 metacarpophalangeal (M...

2025-10-16 | MTBLS1645 | MetaboLights
UnknownActivating Inducible T-cell Costimulator Yields Antitumor Activity Alone and in Combination with Anti-PD-1 Checkpoint Blockade.
Not available
S-EPMC10430783 | biostudies-literature
UnknownFirst-in-human phase 1 study of the ICOS agonist feladilimab on patients with advanced solid tumors.
Not available
S-EPMC12352173 | biostudies-literature
TranscriptomicsGene expression profiles in white blood cells of volunteers exposed to a 50 Hz electromagnetic field
Consistent and independently replicated laboratory evidence to support a causative relationship between environmental exposure to extremely low frequency electromagnetic fields (ELF-EMF) at power line frequencies and the associated increase in risk of childhood leukaemia has not been obtained. In pa...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-GEOD-35999 | biostudies-arrayexpress
GenomicsEGAS00001001204-sc-20150415 - samples
Development of a method for separation and parallel sequencing of the genomes and transcriptomes of single cells.
EGAD00001001332 | EGA
GenomicsG&T-seq: parallel sequencing of the genomes and transcriptomes of single cells
The ability to simultaneously sequence the genome and transcriptome of the same single cell offers a powerful means to dissect functional genetic heterogeneity at the cellular level. Here we describe G&T-seq, a method for separating and sequencing genomic DNA and full-length mRNA from single cells. ...
EGAS00001001204 | EGA
UnknownGermline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer.
Not available
S-EPMC4338615 | biostudies-literature
UnknownCommon variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Not available
S-EPMC2893806 | biostudies-literature
UnknownBreast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.
Not available
S-EPMC3387216 | biostudies-literature
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