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TranscriptomicsMKL1-dependent tenascin-C transcription
The aim of the experiment is to investigate whether megakaryoblastic leukemia factor-1 (MKL1) induces tenascin-C in normal mammary epithelial HC11 and tumor mammary epithelial 4T1 cell lines, as well as to identify other genes that are transcriptionally regulated by MKL1. For this purpose, we compar...
ORGANISM(S): Mus musculus 
2011-06-10 | E-MEXP-3232 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
We have previously shown that HC11 mammary epithelial cells react strongly to the overexpression of megakaryoblastic leukemia-1 (Mkl1) with induction of tenascin-C expression. The present study was designed to find genes co-regulated with tenascin-C by Mkl1 in a SAP domain-dependent manner and witho...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-44907 | biostudies-arrayexpress
MetabolomicsUltra-High Mass Resolving Power, Mass Accuracy, and Dynamic Range MALDI Mass Spectrometry Imaging by 21-T FT-ICR MS

Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy and dynamic range. Fourier transform ion cyclotron resonance mass sp...

2022-01-28 | MTBLS3154 | MetaboLights
TranscriptomicsBilberries reduce low-grade inflammation and subacute endotoxemia in individuals with features of metabolic syndrome - microarray/QPCR profiling of dietary effects of bilberries in PBMCs
Obesity and its consequences on cardiometabolic health have been associated to low-grade inflammation. The most diverse source of dietary anti-inflammatory compounds is polyphenols and especially anthocyanins, which are major polyphenols in bilberries (Vaccinium myrtillus). We investigated the effec...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-34145 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Xenopus tropicalis tadpole tail tissue regeneration following removal
In this experiment, we show transcription profiling of the Xenopus tropicalis tadpole tail tissue regeneration following removal. The tail tissues include its spinal cord, notochord, muscle, and dorsal aorta. We characterized the early, intermediate, and late stages of Xenopus tropicalis tail regene...
ORGANISM(S): Xenopus tropicalis 
2010-10-01 | E-MEXP-2420 | biostudies-arrayexpress
UnknownDevelopment of a child and family centred outcome measure for children and young people with life-limiting and life-threatening conditions: progress to date on the Children's Palliative Care Outcome Scale (C-POS:UK).
Not available
S-EPMC11650473 | biostudies-literature
TranscriptomicsIdentification of megakaryoblastic leukemia-1 (Mkl1) target genes in 4T1 mammary carcinoma cells
The present study was designed to identify Mkl1 target genes whose expression requires either the B1 site of Mkl1 and serum response factor (SRF), respectively, or the SAP domain of Mkl1. For this purpose, we obtained the transcriptomes of four stable 4T1 cell lines that either overexpress full leng...
ORGANISM(S): Mus musculus 
2016-07-15 | E-GEOD-59459 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of individual human oocytes and embryos
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-MEXP-3870 | biostudies-arrayexpress
UnknownDynamic of CSF and serum biomarkers in HIV-1 subtype C encephalitis with CNS genetic compartmentalization-case study.
Not available
S-EPMC5441962 | biostudies-literature
TranscriptomicsHigh-fat diet induced gene expression changes in mouse retina may be prevented by introducing bilberries in diet
Obesity and diabetes associated visual impairment and vascular dysfunctions are increasing reasons for vision loss. The detailed mechanisms in these diseases are still largely unknown, but mice models have been useful to study these mechanisms and explore the detailed effects of potential compounds....
ORGANISM(S): Mus musculus 
2012-09-08 | E-GEOD-34154 | biostudies-arrayexpress
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