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MetabolomicsMetabolomics of bovine uterine fluid at the onset of conceptus elongation
Not available
ORGANISM(S): Bos taurus 
ST000335 | MetabolomicsWorkbench
TranscriptomicsComparison of the transcriptomes of tfIIs vs Col-0
Testing the consequences of the absence of the transcript elongation factor TFIIS on the transcriptome in Arabidopsis. Keywords: Comparison of mutant and wildtype Four replicate RNA extractions were performed of each genotype using independent pools of plants. Samples were hybridized in two dye-swap...
ORGANISM(S): Arabidopsis thaliana 
2010-04-03 | E-GEOD-10663 | biostudies-arrayexpress
TranscriptomicsRoles for the Transcription Elongation Factor NusA in Both DNA Repair and Damage Tolerance Pathways in Escherichia coli
Here we report our observations that have led us to propose that the transcription elongation factor NusA promotes a novel class of transcription-coupled repair (TCR) in addition to its previously proposed role in recruiting translesion synthesis (TLS) DNA polymerases to gaps encountered during tran...
ORGANISM(S): Escherichia coli 
2010-07-14 | E-GEOD-22829 | biostudies-arrayexpress
TranscriptomicsDistinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments
During translation elongation, the ribosome ratchets along its mRNA template, incorporating each new amino acid and translocating from one codon to the next. The elongation cycle requires dramatic structural rearrangements of the ribosome. We show here that deep sequencing of ribosome-protected mRNA...
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-10 | E-GEOD-58321 | biostudies-arrayexpress
TranscriptomicsTransformation of elongation factor 1Bdelta into heat shock response transcription factor by alternative splicing
Protein translation factors play crucial roles in a variety of stress responses. Here, we show that the eukaryotic elongation factor 1Bdelta (eEF1Bdelta) changes its structure and function from a translation factor into a heat shock response transcription factor by alternative splicing. While eEF1Bd...
ORGANISM(S): Homo sapiens 
2011-04-12 | E-GEOD-28506 | biostudies-arrayexpress
TranscriptomicsThe RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.
Deletion of the flap loop in the Rp2 subunit of human RNAPII did not alter the ability of human RNAPII to initiate transcription or elongate the initiated transcripts in vivo and in vitro, and was also dispensable for elongation factor-mediated enhancement and inhibition of transcript elongation in ...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-29734 | biostudies-arrayexpress
TranscriptomicsAnalyzing the role of transcription elongation factors Spt4-5 in splicing
A set of 22 expts. aimed at identifying splicing events dependent upon on the Spt4-5 transcription elongation factors in yeast. Four spt mutants and an mRNA capping mutant were analyzed four times each, including biological and technical (dye-swap) replicates. Two wt vs wt expts. were also perform...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-09 | E-GEOD-1610 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast with a C-terminal deletion of the RNA polymerase II elongation factor Spt6 or overexpression of Spt6
Influence of a C-terminal deletion of the RNA polymerase II elongation factor Spt6 on the transcription of the yeast genome. In parallel the influence of a Spt6 overexpression on gene expression is analyzed.
ORGANISM(S): Saccharomyces cerevisiae 
2009-04-08 | E-MEXP-2123 | biostudies-arrayexpress
TranscriptomicsA triple-HLH/bHLH Cascade Controls Cell Elongation Downstream of Multiple Hormonal and Environmental Signaling Pathways
The environmental and endogenous signals, light, temperature, brassinosteroid (BR), and gibberellin (GA), regulate cell elongation largely by controlling the expression of the PRE family helix-Loop-helix (HLH) factors, which promote cell elongation by interacting antagonistically with another HLH fa...
ORGANISM(S): Arabidopsis thaliana 
2015-01-01 | E-GEOD-41766 | biostudies-arrayexpress
TranscriptomicsTEF-seq/NET-seq applied to factors Rpb3, Paf1, Spt6, Spt16, Cet1, Pcf11, Ssu72, Set2
Here we adapt native elongating transcript sequencing (NET-seq) to develop transcription elongation factor associated nascent elongating transcript sequencing (TEF-seq). In this the RNA polymerase II (Pol2) transcription elongation complex (TEC) is immunoprecipitated via associated transcription elo...
ORGANISM(S): Saccharomyces cerevisiae 
2021-01-18 | E-MTAB-4568 | biostudies-arrayexpress
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