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MetabolomicsMetabolomics of bovine uterine fluid at the onset of conceptus elongation
Not available
ORGANISM(S): Bos taurus 
ST000335 | MetabolomicsWorkbench
TranscriptomicscDNA microarray expression profile during fiber elongation between G. hirsutum and G. barbadense
Sea-island cotton (Gossypium barbadense L.) has superior fiber quality properties such as length, fineness and strength, while Upland cotton (Gossypium hirsutum L.) is characterized by high yield. To reveal features of Upland cotton and Sea-island cotton fiber cells, differential genes expression pr...
ORGANISM(S): Gossypium hirsutum 
2012-05-23 | E-GEOD-18028 | biostudies-arrayexpress
TranscriptomicsTEF-seq/NET-seq applied to factors Rpb3, Paf1, Spt6, Spt16, Cet1, Pcf11, Ssu72, Set2
Here we adapt native elongating transcript sequencing (NET-seq) to develop transcription elongation factor associated nascent elongating transcript sequencing (TEF-seq). In this the RNA polymerase II (Pol2) transcription elongation complex (TEC) is immunoprecipitated via associated transcription elo...
ORGANISM(S): Saccharomyces cerevisiae 
2021-01-18 | E-MTAB-4568 | biostudies-arrayexpress
TranscriptomicsThe RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.
Deletion of the flap loop in the Rp2 subunit of human RNAPII did not alter the ability of human RNAPII to initiate transcription or elongate the initiated transcripts in vivo and in vitro, and was also dispensable for elongation factor-mediated enhancement and inhibition of transcript elongation in ...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-29734 | biostudies-arrayexpress
TranscriptomicsAnalyzing the role of transcription elongation factors Spt4-5 in splicing
A set of 22 expts. aimed at identifying splicing events dependent upon on the Spt4-5 transcription elongation factors in yeast. Four spt mutants and an mRNA capping mutant were analyzed four times each, including biological and technical (dye-swap) replicates. Two wt vs wt expts. were also perform...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-09 | E-GEOD-1610 | biostudies-arrayexpress
TranscriptomicsThe RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells and Primes Future Gene Activation
Enhancers play a central role in precisely regulating the spatiotemporal expression of developmentally regulated genes. The molecular mechanisms and factors required for controlling the inactive or poised enhancers and their function in future gene activation remain elusive. Here, we have identified...
ORGANISM(S): Mus musculus 
2012-12-30 | E-GEOD-38148 | biostudies-arrayexpress
Transcriptomics4sUDRB-seq: measuring transcription elongation and initiation genomewide
A new method to measure elongation and intitiation rates Reversal inhibition of transcription with DRB and tagging newly transcribed RNA with 4-thiouridine (4sU)
ORGANISM(S): Homo sapiens 
2014-05-09 | E-GEOD-57116 | biostudies-arrayexpress
UnknownThiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4.
Not available
S-EPMC3245911 | biostudies-literature
TranscriptomicsRNA-Seq of control and ELL2-depleted MPC11 plasmacytoma cell lines
We report RNA-Seq data from MPC11 plasmacytoma cell lines transduced with either control hairpins (shGFP) or hairpins targeting the transcriptional elongation factor ELL2. ELL2 has been identified as regulating the alternative splicing and polyadenylation of immunoglobulin pre-mRNA, and is highly e...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40285 | biostudies-arrayexpress
TranscriptomicsExamination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-
Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathways we analyzed the brain of B6J-nmf205-/- mice in which neuronal elongation complexes are stall...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-79926 | biostudies-arrayexpress
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