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TranscriptomicsFactors underlying variable DNA methylation in a human community cohort
Epigenetics is emerging as an attractive mechanism to explain the persistent genomic embedding of early-life experiences. Tightly linked to chromatin, which packages DNA into chromosomes, epigenetic marks primarily serve to regulate the activity of genes. DNA methylation is the most accessible and c...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-37008 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of BEAF-32A and BEAF-32B in Drosophila embryos
ChIP-chip analysis of BEAF binding sites in Drosophila embryos using three antibodies: one that recognize both BEAF-32A and BEAF-32B, one specific for BEAF-32A and one specific for BEAF-32B
ORGANISM(S): Drosophila melanogaster 
2009-06-26 | E-TABM-597 | biostudies-arrayexpress
TranscriptomicsDistinct DNA methylation patterns of cognitive impairment and Trisomy 21 in Down Syndrome
The presence of an extra whole or part of chromosome 21 in people with Down syndrome (DS) is associated with multiple neurological changes, including pathological aging that often meets the criteria for Alzheimer’s Disease (AD). While the mechanism underlying these changes is unknown, it has been hy...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-50586 | biostudies-arrayexpress
TranscriptomicsAdditional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array
Background: Measurement of genome-wide DNA methylation (DNAm) has become an important avenue for investigating potentially functional changes in various pathological conditions. Illumina Infinium is a relatively inexpensive and user-friendly DNAm microarray platform used by many researchers to measu...
ORGANISM(S): Homo sapiens 
2013-03-04 | E-GEOD-42409 | biostudies-arrayexpress
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