Embryonic stem cells (escs)

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Genomics (2305)
Unknown (1672)
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Proteomics (109)
Methylation profiling (84)
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Organisms

Mus musculus (1740)
Homo sapiens (394)
Aerococcus urinae NBRC 15544 = CCUG 36881 (101)
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Canis lupus familiaris (101)
Carya cathayensis (101)
Macaca mulatta (29)
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synthetic construct (3)
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artificial sequences (1)
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Organisms

Mus musculus (1298)
Homo sapiens (216)
Macaca mulatta (13)
Bos taurus (12)
Rattus norvegicus (9)
Gallus gallus (8)
Sus scrofa (7)
Callithrix jacchus (6)
Macaca fascicularis (5)
Mus musculus musculus x Mus musculus castaneus (2)
Mus (2)
Monodelphis domestica (1)
Mammalia (1)
Oryctolagus cuniculus (1)
Schmidtea mediterranea (1)
Ovis aries (1)
Mus musculus domesticus (1)

Repository

ENA (1744)
geo (1310)
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pride (101)
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Tissue

Embryonic stem cell (79)
Cell culture (35)
Embryo (13)
Stem cell (5)
Fibroblast (4)
Early embryonic cell (3)
Blastocyst (1)
Cell suspension culture (1)
Dermal fibroblast (1)
Embryonic fibroblast (1)
Embryonic germ cell (1)
Epiblast (1)
Germ cell (1)
HESC cell (1)
Multipotent stem cell (1)
Permanent cell line cell (1)
Pluripotent stem cell (1)
Primary cell (1)

Disease

Disease free (7)
Not Applicable (1)
Not applicable (1)
Normal (1)
Acute leukemia (1)
Osteoporosis (1)

Technology Type

Mass Spectrometry (101)
Shotgun proteomics (54)
Affinity purification coupled with mass spectrometry proteomics (32)
Bottom-up proteomics (13)
Data-dependent acquisition (8)
Gel-based experiment (8)
SRM/MRM (3)
Affinity proteomics (2)
Data-independent acquisition (2)
Illumina HiSeq 2000 (1)
Mass spectrometry (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
DiaPASEF (1)
Glycoproteomics (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2000 (28)
Illumina HiSeq 2500 (26)
NextSeq 500 (24)
Illumina NovaSeq 6000 (22)
Illumina Genome Analyzer IIx (9)
Illumina HiSeq 4000 (8)
NextSeq 2000 (5)
Illumina HiSeq 1500 (4)
Illumina Genome Analyzer II (2)
Illumina NovaSeq X (2)
Illumina HiSeq 1000 (2)
Illumina MiSeq (2)
NextSeq 550 (2)
Deeptools, macs3 (1)
Not (1)
BD FACSAria cell sorter (1)
HiSeq X Five (1)
Fluidigm C1 (1)
Linux computer (1)
Linux Beowulf cluster; AMD Opteron Linux Beowulf cluster; AMD Opteron 6168 (1)
Affymetrix Fluidics Station 400 (1)
N/a (1)
Ion Torrent Proton (1)
HiSeq X Ten (1)
Illumina NextSeq 500 (1)
Illumina HiSeq 3000 (1)
Q Exactive HF-X (1)
Q Exactive Plus (1)
Q Exactive (1)

Publication Date

2015 (239)
2014 (202)
2013 (194)
2016 (184)
2022 (141)
2021 (121)
2023 (119)
2025 (118)
2020 (118)
2012 (118)
2018 (106)
2026 (101)
2024 (101)
2019 (100)
2017 (89)
2011 (89)
2010 (82)
2009 (36)
2008 (23)
2007 (10)
2006 (4)
2005 (2)

CHEBI ID

CHEBI:58527 (1)
CHEBI:18083 (1)
CHEBI:165827 (1)
CHEBI:165824 (1)
CHEBI:136461 (1)
CHEBI:17759 (1)
CHEBI:35145 (1)
CHEBI:35766 (1)
CHEBI:133693 (1)
CHEBI:133677 (1)
CHEBI:84562 (1)
CHEBI:84814 (1)
CHEBI:84532 (1)
CHEBI:84527 (1)
CHEBI:138529 (1)
CHEBI:74534 (1)
CHEBI:60312 (1)
CHEBI:37564 (1)
CHEBI:143243 (1)
CHEBI:165860 (1)
CHEBI:26073 (1)
CHEBI:74990 (1)
CHEBI:36315 (1)
CHEBI:68434 (1)
CHEBI:145970 (1)
CHEBI:133515 (1)
CHEBI:78266 (1)
CHEBI:73218 (1)
CHEBI:78261 (1)
CHEBI:82753 (1)

Metabolite Name

Thymidine 5'-monophosphate (1)
Sphingadienine (1)
Ribulose/xylulose 5-phosphate (1)
Nicotinate ribonucleoside (1)
Nicotinate (1)
Glycerophosphoserine (1)
Glycerophosphoinositol (1)
Glucuronate 1-phosphate (1)
Cysteine sulfinic acid (1)
Alpha-ketoglutaramate (1)
2-palmitoleoyl-GPC (16:1) (1)
1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6) (1)
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6) (1)
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6) (1)
1-methyladenine (1)
1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1) (1)
(3'-5')-guanylyluridine (1)
(3'-5')-cytidylyluridine (1)
Phenol red (1)
Penicillin G (1)
Gamma-glutamylcysteine (1)
3-hydroxypalmitoylcarnitine (1)
2'-O-methyluridine (1)
Oleoylcholine (1)
Palmitoylcholine (1)
1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) (1)
1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) (1)
N-acetylglucosamine/N-acetylgalactosamine (1)
Ribulose/xylulose (1)
Pterin (1)

First Public Date

2014 (242)
2022 (157)
2024 (148)
2025 (129)
2023 (128)
2020 (125)
2021 (117)
2017 (111)
2019 (110)
2018 (110)
2026 (104)
2015 (94)
2016 (93)
2013 (76)

Modification

N6 (2)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (328)
ChIP-seq (187)
RNA-seq of coding RNA (185)
Methylation profiling by high throughput sequencing (37)
Other (21)
Methylation profiling by array (16)
RNA-seq of coding RNA from single cells (15)
RNA-seq of non coding RNA (12)
Unknown experiment type (10)
Cell line - High-throughput sequencing (9)
ChIP-chip by tiling array (8)
ATAC-seq (8)
Comparative genomic hybridization by array (7)
High-throughput sequencing (4)
DNA-seq (4)
RNA-seq of total RNA (4)
ChIP-chip by array (3)
Genotyping by array (2)
Transcription profiling by RT-PCR (2)
Hi-C (2)
RIP-seq (2)
CUT&RUN (2)
GRO-seq (1)
FAIRE-seq (1)
Baseline (1)
Translation profiling (1)
Animal - High-throughput sequencing (1)
Trajectory (1)
RNAi profiling by array (1)
4C (1)

Release Date

2015 (288)
2014 (260)
2013 (227)
2016 (224)
2012 (160)
2020 (147)
2018 (144)
2021 (142)
2017 (132)
2022 (116)
2011 (115)
2023 (111)
2019 (107)
2010 (104)
2024 (76)
2025 (75)
2009 (53)
2008 (30)
2026 (18)
2007 (13)
2005 (3)
2006 (2)
2003 (1)

Lab affiliation

Department of Medicine, Columbia University Irving Medical Center (4)
1. Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel 2. Computer Science Department, Technion - Israel Institute of Technology, Haifa 320003, Israel (3)
Molecular Biology, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands (3)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark (3)
Babraham Research Campus, Cambridge, UK (2)
Center for Genomic Regulation Differentiation and Cancer Passeig Maritim 37-49 Barcelona 08003 SPAIN (2)
Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen, Copenhagen, Denmark. (2)
Ottawa Hospital Research Institute (2)
1 Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu225009, P.R. China 2 Key Laboratory of Animal Breeding Reproduction and Molecular Design for Jiangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu225009, P.R. China (1)
1. Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel. 2. Computer Science Department, Technion - Israel Institute of Technology, Haifa 320003, Israel. (1)
Asan Medical Center, Clinical Proteomics Core, Republic of Korea (1)
Babraham Institute (1)
Babraham Istitute (1)
Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China (1)
CNRS UMR7242, Biotechnology and Cell Signaling, 300 Bd Sébastien Brant, 67412 Illkirch Cedex, France University of Strasbourg (1)
Cell Fate Engineering and Therapeutics Lab, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Republic of Singapore (1)
Cell and Regenerative Biology, University of Wisconsin-Madison (1)
Center for Genomic Regulation (CRG) (1)
Center for Genomic Regulation (CRG) University Pompeu Fabra (UPF) (1)
Center of Growth Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, China. (1)
Centre for Epigenetics and Department of Biochemistry and Molecular Biology, University of Southern Denmark Campusvej 55 DK-5230 Odense M, Denmark (1)
Chancellor's Professor of Bioengineering University of California Los Angeles (1)
Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet SE 17177 Stockholm, Sweden. Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow, 119146, Russia. (1)
Department of Anatomy and Developmental Biology, Australian Regenerative Medicine Institute, Monash University, Australia (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany (1)
Department of Biomedical Science E-04, Florey building Firth Court, Western Bank University of Sheffield Sheffield, S10 2TN United Kingdom (1)
Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (1)
Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA. (1)
Department of Genetics, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Jerusalem, Israel (1)

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Pedigreed Primate Embryonic Stem Cells Express Homogeneous Familial Gene Profiles

Pedigreed primate ESCs display homogeneous and reliable expression profiles. These similarities to mouse ESCs suggest that heterogeneities found among hESCs result from their disparate origins rather than intrinsic biological limitations with primate embryonic stem cells. Keywords: different nhpESC ...

ORGANISM(S): Macaca mulatta

2008-04-14 | E-GEOD-7534 | biostudies-arrayexpress

Embryonic stem cells exhibit mRNA isoform-specific translational regulation

Investigation of the differential translation rates of individual mRNA variants in embryonic stem cells (ESCs) and in ESC-derived neural precursor cells (NPCs) using polysome profiling coupled to RNA sequencing. Mouse ESCs were differentiated into Sox1-positive neural precursor cells (NPCs). One rep...

ORGANISM(S): Mus musculus

2016-01-26 | E-GEOD-73467 | biostudies-arrayexpress

Transcription profiling of mouse embryonic stem cells (ESCs) differentiation into embyroid bodies (EBs

Stem cell differentiation is known to involve changes in RNA expression, but little is known about translational control during differentiation. We comprehensively profiled gene expression during differentiation of embryonic stem cells (ESCs) into embyroid bodies (EBs) by integrating conventional t...

ORGANISM(S): Mus musculus

2008-06-20 | E-GEOD-9563 | biostudies-arrayexpress

Genome-wide mapping of miRNAs expressed in embryonic stem cells and pluripotent stem cells generated by different reprogramming strategies

We report the miRNA profiling in MEF cells, ES cells and three Pluripotent Stem Cells obtained by three different reprogramming approaches from MEF cells based on Solexa sequencing. iPS cells are reprogrammed by four factors (OSKM) from MEF cells. NT-ESCs were established by reprogramming MEF cells ...

ORGANISM(S): Mus musculus

2014-07-05 | E-GEOD-52950 | biostudies-arrayexpress

Gene-expression profile of human embryonic germ cells

Gene-expression profile of human embryonic germ cells (EGCs), primordial germ cells (PGCs), embryonal carcinoma cells (ECCs), pluripotent embryonic stem cells (ESCs) and induced pluripotent stem cells (IPSCs)

ORGANISM(S): Homo sapiens

2018-06-28 | E-MTAB-6851 | biostudies-arrayexpress

Effect of L-Proline on mouse embryonic stem cells (ESCs)

We found that the non-essential amino acid L-Proline (L-Pro) acts as a signaling molecule that promotes the conversion of embryonic stem cells (ESCs) into mesenchymal-like, spindle-shaped, highly motile, invasive pluripotent stem cells. This embryonic stem cell-to-mesenchymal-like transition (esMT) ...

ORGANISM(S): Mus musculus

2013-09-05 | E-GEOD-50603 | biostudies-arrayexpress

Discovery of novel imprinted genes by transcriptional analysis of parthenogenetic embryonic stem cells

Parthenogenetic embryonic stem cells (PESCs) may have future utility in cell replacement therapies. We examined genome-wide mRNA expression profiles of monkey PESCs relative to ESCs derived from fertilized embryos. Several known paternally-imprinted genes were in the highly down-regulated group in P...

ORGANISM(S): Macaca mulatta

2010-07-07 | E-GEOD-17964 | biostudies-arrayexpress

FungenES: FunGenES_UKOE-4: Functional characterization and transcriptome analysis of embryonic stem cells-derived contractile smooth muscle cells

This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the EuropeanUnion, http://www.fungenes.org). The experiment was conducted at University of Cologne, Cologne, Germany. Goal of the experiment is a...

ORGANISM(S): Mus musculus

2011-02-25 | E-TABM-1123 | biostudies-arrayexpress

Gene expression profiles of mouse embryonic stem cells (mESCs) after genetic depletion of Id1 and knock-down of Zrf1

Id proteins are dominant negative regulators within the HLH family of proteins. In embryonic stem cells (ESCs), Id1 and Id3 maintain the pluripotent state by preventing neural differentiation. The Id1-interacting protein Zrf1 plays a crucial role as a chromatin-bound factor in specification of the n...

ORGANISM(S): Mus musculus

2014-11-05 | E-GEOD-58627 | biostudies-arrayexpress

Genome-wide Definition of Promoter and Enhancer Usage During Neural Induction of Human Embryonic Stem Cells [CAGE-seq]

Genome-wide mapping of transcriptional regulatory elements are essential tools for the understanding of the molecular events orchestrating self-renewal, commitment and differentiation of stem cells. We combined high-throughput identification of nascent, Pol-II-transcribed RNAs by Cap Analysis of Gen...

ORGANISM(S): Homo sapiens

2015-05-21 | E-GEOD-61264 | biostudies-arrayexpress

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