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ProteomicsA Novel High-Throughput Immunoaffinity LC-MS/MS Assay for P III-NP and other Fragments of Type III Procollagen in Human Serum
The amino-terminal propeptide of type III procollagen (P-III-NP) is used with IGF-I to detect the illicit use of growth hormone and to monitor growth hormone therapy. However, the only currently available assays for P-III-NP are immunoassays, which are not well harmonized. In addition, other fragmen...
ORGANISM(S): Homo Sapiens 
2024-10-28 | PXD052245 | panorama
ProteomicsEvaluation of Linearity, Lower Limit of Measurement Interval and Imprecision
Introduction Glucagon and oxyntomodulin are peptide hormones differentially released from proglucagon that function in regulating blood glucose concentrations. Their overlapping amino acid sequences make the development of specific immunoassays difficult, but the specificity of liquid chromatography...
ORGANISM(S): Homo Sapiens 
PXD041410 | panorama
ProteomicsMetrologically traceable quantification of three apolipoprotein E isoforms in cerebrospinal fluid
Apolipoprotein E (apoE) is a 317-amino-acid long glycoprotein with three common isoforms (apoE2, apoE3, and apoE4) encoded by three apoE alleles (ε2, ε3, and ε4). These polymorphic forms arise from single amino acid substitutions with Cys and Arg interchanged at positions 112 and 158 (mature protein...
ORGANISM(S): Homo Sapiens 
PXD038803 | panorama
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