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MetabolomicsMetabolic Biomarkers of Treatment-Resistant Schizophrenia and Cognitive Correlates: Insights from a Machine Learning

Metabolic Biomarkers of Treatment-Resistant Schizophrenia and Cognitive Correlates: Insights from a Machine Learning

2027-02-05 | MTBLS14005 | MetaboLights
MetabolomicsPlasma metabolomic and lipidomic signatures characteristic of treatment non-response in rheumatoid arthritis

Objectives: This study aimed to investigate plasma metabolomic and lipidomic profiles in rheumatoid arthritis (RA) to identify potential biomarkers for distinguishing treatment responses.

Methods: Plasma samples w...

2026-06-02 | MTBLS13238 | MetaboLights
MetabolomicsTemporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment
Lung cancer causes more deaths in men and women than any other cancer related disease. Currently, few effective strategies exist to predict how patients will respond to treatment. We evaluated the serum metabolomic profiles of 25 lung cancer patients undergoing chemotherapy ± radiation to evaluate t...
2017-01-19 | MTBLS200 | MetaboLights
MetabolomicsUntargeted 1 H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant Schizophrenia patients: a pilot study

Schizophrenia is a severe psychiatric disorder impacting roughly 1% of individuals. The effectiveness of antipsychotic therapy greatly varies, with around 30% of patients categorised as treatment-resistant (TRS). TRS is characterised by a lack of response to at least two clinical trials invo...

2025-10-01 | MTBLS12709 | MetaboLights
MetabolomicsPlasma metabolomic and lipidomic signatures characteristic of treatment non-response in rheumatoid arthritis

Objectives: This study aimed to investigate plasma metabolomic and lipidomic profiles in rheumatoid arthritis (RA) to identify potential biomarkers for distinguishing treatment responses.

Methods: Plasma samples...

2026-06-02 | MTBLS13243 | MetaboLights
MetabolomicsMetabolomics analysis of liver reveals profile disruption in bovines upon steroid treatment
INTRODUCTION: The surveillance of illegal anabolic practices in bovine meat production is necessary to guarantee consumers’ health. Screening strategies based on the recognition of indirect biological effects are considered by the community as promising tools to overcome some limitations of classica...
2018-05-08 | MTBLS436 | MetaboLights
MetabolomicsInvestigation of Brazilian grape juice metabolomic profile changes caused by methyl jasmonate pre-harvest treatment

Grape juice is a major source of potential health-promoting bioactive polyphenols, especially for children and those who do not consume wine. Since the subtropical climate may negatively affect the concentrations of grape polyphenols, especially anthocyanins, elicitors such as methyl jasmonate (M...

2022-06-28 | MTBLS2401 | MetaboLights
MetabolomicsMetabolic fingerprinting reveals a novel candidate biomarker for prednisolone treatment in cattle
The use of glucocorticoids as growth promoters for meat-producing animals is strictly regulated within the European Union. However, in the past few years, a higher frequency of non-compliant bovine urine samples for prednisolone has been noticed, which could not be directly related to fraudulent use...
2017-01-12 | MTBLS185 | MetaboLights
MetabolomicsPlasma Metabolome Analysis for Predicting Antiviral Treatment Efficacy in Chronic Hepatitis B: Diagnostic Biomarkers and Therapeutic Insights
The early and accurate identification of predictive biomarkers for antiviral treatment efficacy remains a significant clinical challenge, particularly in the management of chronic hepatitis B (CHB). This study aimed to assess whether the plasma metabolome could reliably predict the success of antivi...
2024-07-10 | MTBLS10401 | MetaboLights
MetabolomicsCoral symbiotic bacterial community and metabolites changes under thermal stress: A case of laboratory experiment with heating treatment
Coral bleaching and coral reef degradation become severe as the surface seawater temperature rises. Much research to date has focused on the bacterial community composition properties within the coral holobiont, but less attention has been paid to the interactions of bacteria and corals under therma...
2022-10-27 | MTBLS5272 | MetaboLights
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