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TranscriptomicsThe Vasa homolog RDE-12 engages target mRNA and a secondary-Argonaute WAGO-1 to promote RNAi in C. elegans
Argonaute proteins (AGOs) are key nuclease effectors of RNA interference (RNAi) [1]. Although purified AGOs can mediate a single round of target-RNA cleavage in vitro, accessory factors are required for siRNA loading and to achieve multiple-target turnover [2, 3]. To identify AGO co-factors we immun...
ORGANISM(S): Caenorhabditis elegans 
2014-06-24 | E-GEOD-54396 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis CAF-1 depletion/gamma-irradiation
CAF-1 is involved in nucleosome assembly following DNA replication and nucleotide excision repair. In Arabidopsis thaliana, the 3 CAF-1 subunits p150, p60 and p48 are encoded by FAS1, FAS2 and, most likely, MSI1, respectively.fas mutants exhibited increased levels of DNA double-strand breaks, a G2 p...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-5043 | biostudies-arrayexpress
ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000540 | BioModels
ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 2
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 2 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000541 | BioModels
Unknownα-Tocopherol suppresses hepatic steatosis by increasing CPT-1 expression in a mouse model of diet-induced nonalcoholic fatty liver disease.
Not available
S-EPMC7909598 | biostudies-literature
UnknownEffects of the COVID-19 pandemic on gastroenterological surgeries in 2020: A study using the National Clinical Database of Japan.
Not available
S-EPMC10154870 | biostudies-literature
UnknownInvolvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.
Not available
S-EPMC4054430 | biostudies-literature
UnknownIntraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor.
Not available
S-EPMC9214486 | biostudies-literature
UnknownOptimal target blood pressure in elderly with septic shock (OPTPRESS) trial: study protocol for a randomized controlled trial.
Not available
S-EPMC9509562 | biostudies-literature
UnknownSurgical outcomes in gastroenterological surgery in Japan: Report of the National Clinical Database 2011-2019.
Not available
S-EPMC8452469 | biostudies-literature
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