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ProteomicsEndocytic Turnover of Endothelial Cell-Membrane Proteins as a Driver of Blood Brain Barrier Specialization and Dysfunction
The blood-brain barrier (BBB), formed primarily by specialized brain endothelial cells (BEC), exerts essential functions for proper brain activity, including nutrient transport, signal transduction, immune cell transmigration and pathogen restriction. While these functions are known to be regulated ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-05-15 | PXD067112 | Pride
Blood-brain barrier Brain endothelial cells Endocytic turnover rate 
UnknownUbiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin.
Not available
S-EPMC5706963 | biostudies-literature
UnknownAccurate measurement of fast endocytic recycling kinetics in real time.
Not available
S-EPMC6983720 | biostudies-literature
UnknownEarly-arriving Syp1p and Ede1p function in endocytic site placement and formation in budding yeast.
Not available
S-EPMC2777095 | biostudies-literature
UnknownAn intrinsic mechanism of secreted protein aging and turnover.
Not available
S-EPMC4640737 | biostudies-literature
ModelsGiantsosAdams2013 - Growth of glycocalyx under static conditions
Giantsos-Adams2013 - Growth of glycocalyx under static conditions This model is described in the article: Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Giantsos-Adams KM, Koo AJ, Song...
2024-09-02 | BIOMD0000000830 | BioModels
ModelsGiantsos-Adams2013 - Growth of glycocalyx under static conditions
Giantsos-Adams2013 - Growth of glycocalyx under static conditions This model is described in the article: Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Giantsos-Adams KM, Koo AJ, Song S, Sakai J, Sankaran J, Shin JH, Garcia-Carde...
2016-09-28 | MODEL1609100001 | BioModels
UnknownCofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide state.
Not available
S-EPMC2064657 | biostudies-literature
UnknownReduction of endocytosis and EGFR signaling is associated with the switch from isolated to clustered apoptosis during epithelial tissue remodeling in Drosophila.
Not available
S-EPMC11472926 | biostudies-literature
ProteomicsThe N-acetylglucosaminyltransferase Radical Fringe contributes to defects in JAG1-dependent turnover and signaling of NOTCH3 CADASIL mutants
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic vascular dementia characterized by age-related degeneration of vascular mural cells and accumulation of a NOTCH3 mutant protein. NOTCH3 functions as a signaling receptor, activating down...
ORGANISM(S): Homo Sapiens (human) 
2024-09-19 | PXD048554 | JPOST Repository
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