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MetabolomicsMetabolomic analysis of metabolic differences between NSD1 wild-type and NSD1 knockout endometrial cancer cells

Metabolomic analysis of metabolic differences between NSD1 wild-type and NSD1 knockout endometrial cancer cells

2026-01-21 | MTBLS13567 | MetaboLights
MetabolomicsPolystyrene nanoparticles promote endometrial cancer development through the ACSS2-mediated reprogramming of arachidonic acid metabolism

Microplastics and nanoplastics are commonly found in our everyday environments. So far, microplastics and nanoplastics have been detected in various tissues and bodily fluids, including hair, sputum, digestive tissue, lungs, blood, and placental tissue. Although some studies indicate that micropl...

2026-02-05 | MTBLS13850 | MetaboLights
MetabolomicsMulti-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
Endometrial cancer (EC) is one of the most common gynecological cancers. Finding biomarkers of EC can support its diagnosis in a non- or minimally-invasive way. In this work, we integrated metabolomics and proteomics for the analysis of multiple types of biosamples to gain a more comprehensive view ...
2022-03-28 | MTBLS3935 | MetaboLights
MetabolomicsOA-HOXB9-ODC1-Polyamine Axis Mediates Metabolic Syndrome Promoting Endometrial Cancer Progression

Metabolic syndrome (MS) is a risk factor for both the development and progression of endometrial cancer (EC); however, the mechanism remains unclear. We found that polyamine metabolites are significantly elevated in the sera and tumor tissues of EC patients with MS (ECWMS). Hyperlipidemia is a cr...

2025-11-08 | MTBLS13106 | MetaboLights
MetabolomicsExposure to Oral Contraceptives Alters Human Endometrial Stem Cells Culture Media Metabolomics
Not available
ORGANISM(S): Homo sapiens 
ST001113 | MetabolomicsWorkbench
ProteomicsHLA-I and HLA-II peptidomes of endometrial cancer
MS data of HLA class I and HLA class II ligandome of human endometrial cancer
ORGANISM(S): Homo Sapiens (human) 
2024-10-31 | PXD050576 | JPOST Repository
TranscriptomicsGene expression in human endometrial cancer tissues and serous papillary endometrial cancer cell line, SPAC-1L, treated by STAT1-siRNA and/or IFN-gamma
Endometrial cancer is one of the most common gynecologic malignancies, and patients with high grade disease, especially serous papillary subtype (SPEC) are often related to the poor outcomes. Recent genome-wide analyses have revealed that SPEC exhibits gene expression profiles that are distinct from...
ORGANISM(S): Homo sapiens 
2014-03-20 | E-GEOD-56026 | biostudies-arrayexpress
TranscriptomicsCOUP-TFII regulates human endometrial stromal genes involved in inflammation
Although the function of COUP-TFII in uterine decidualization has been described in mice, its role in the human uterus remains unknown.To interrogate the role of COUP-TFII in human endometrial function, we utilized a siRNA-mediated loss of function approach in primary human endometrial stromal cells...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-47052 | biostudies-arrayexpress
TranscriptomicsEndometrial methylome of patients without endometriosis
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-73949 | biostudies-arrayexpress
TranscriptomicsReciprocal communication between endometrial stromal cells and macrophages
Endometriosis is an inflammatory disease and bone marrow-derived cells are abundant in endometriotic lesions and in the peritoneal fluid of women with the disease. This study tested the hypothesis that reciprocal communication occurs between macrophages and cultured human endometrial stromal cells ...
ORGANISM(S): Homo sapiens 
2010-07-21 | E-GEOD-19834 | biostudies-arrayexpress
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