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TranscriptomicsRepertoire of miRNAs in epithelial ovarian cancer determined by next generation sequencing of small RNA cDNA libraries
Background: MicroRNAs (miRNAs) are small regulatory RNAs that are implicated in cancer pathogenesis and have recently shown promise as blood-based biomarkers for cancer detection. Epithelial ovarian cancer is a deadly disease for which improved outcomes could be achieved by successful early detectio...
ORGANISM(S): Homo sapiens 
2009-03-12 | E-GEOD-15190 | biostudies-arrayexpress
ProteomicsA targeted strategy for developing proteomic biomarkers: a case study of epithelial ovarian cancer
Protein biomarkers for epithelial ovarian cancer are critical for the early detection of the cancer to improve patient prognosis and for the clinical management of the disease to monitor treatment response and to detect recurrences. Unfortunately, the discovery of protein biomarkers is hampered by t...
ORGANISM(S): Homo Sapiens 
PXD014474 | panorama
ProteomicsEpithelial ovarian cancer biomarker
Protein biomarkers of early stages of disease are critical for managing the disease and improving outcomes. Unfortunately, discovery of protein biomarkers is hampered by the limited availability of assays for sensitive and reproducible quantification of proteins in complex biological matrices such a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-02 | MSV000084048 | MassIVE
TranscriptomicsOvarian Cancer CGH
OBJECTIVES: Amplification of the 11q13 locus is commonly observed in a number of human cancers including both breast and ovarian cancer. Cyclin D1 and EMS1 have been implicated as candidate oncogenes involved in the emergence of amplification at this locus. Detailed analysis of the 11q13 amplicon in...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-16408 | biostudies-arrayexpress
ProteomicsA Proteogenomic View of Synchronous Endometrioid Endometrial and Ovarian Cancer
Purpose: Increasing genomics-based evidence suggests that synchronous endometrial and ovarian cancer (SEOC) represents clonally related primary and metastatic tumors. A systematic analysis of the global protein landscape of SEOCs, heretofore lacking, could reveal functional and disease-specific cons...
ORGANISM(S): Homo sapiens (Human) 
2025-03-11 | PXD059172 | Pride
Ovarian cancer Proteomics Endometrial cancer Synchronous cancer 
TranscriptomicsTranscription profiling of human ovarian tumors and normal ovaries
99 individual ovarian tumors (37 endometrioid, 41 serous, 13 mucinous, and 8 clear cell carcinomas) and 4 individual normal ovary samples, each assayed on an Affymetrix HG_U133A array Experiment Overall Design: 99 individual ovarian tumors (37 endometrioid, 41 serous, 13 mucinous, and 8 clear cell c...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6008 | biostudies-arrayexpress
GenomicsTranscriptome-wide m6A methylome of endometrioid ovarian cancer and ovarian endometriosis
Transcriptome-wide m6A methylome of endometrioid ovarian cancer and ovarian endometriosis
PRJNA807156 | ENA
TranscriptomicsComplement Roles Revealed by Immune Gene Profiling in Endometriosis and Endometriosis-Associated Ovarian Cancer
Mechanisms of immune dysregulation against established tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear cell ovarian tumors may partly derive from endometriosis, a commonly diagnosed chronic inflamma...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-57545 | biostudies-arrayexpress
TranscriptomicsGene expression data of ovarian cancer from Singapore
A collection of 100 ovarian cancer sample gene expression data from Singapore. Frozen archival epithelial ovarian cancer tumors samples from Department of Obstetrics & Gynecology, National University of Singapore dated from 2006 to 2014 were collected and subjected to microarray analysis.
ORGANISM(S): Homo sapiens 
2016-01-10 | E-GEOD-69207 | biostudies-arrayexpress
TranscriptomicsClaudin-7 is frequently overexpressed in ovarian cancer and promotes invasion
Claudins are tight junction proteins that are involved in tight junction formation and function. Previous studies have shown that claudin-7 is frequently upregulated in epithelial ovarian cancer (EOC) along with claudin-3 and claudin-4. Here, we investigate in detail the expression patterns of claud...
ORGANISM(S): Homo sapiens 
2012-09-19 | E-GEOD-26055 | biostudies-arrayexpress
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