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TranscriptomicsTranscriptome partitioning for mRNA translation in hypoxia
Protein synthesis belongs to the most energy consuming processes in the cell. Lowering oxygen tension below normal (hypoxia) causes a rapid inhibition of global mRNA translation due to the decreased availability of energy. Interestingly, subsets of mRNAs pursue active translation under such circumst...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-49029 | biostudies-arrayexpress
UnknownFormalin evokes calcium transients from the endoplasmatic reticulum.
Not available
S-EPMC4398422 | biostudies-literature
UnknownFunctional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies.
Not available
S-EPMC4622715 | biostudies-literature
GenomicsChronic endoplasmatic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release
Chronic endoplasmatic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release
PRJNA1013325 | ENA
UnknownCHST6 mutation screening and endoplasmatic reticulum stress in macular corneal dystrophy.
Not available
S-EPMC5707101 | biostudies-literature
TranscriptomicsExpression data from human colorectal cancer cell line
Tumor suppressor candidate-3 (TUSC3/N33) is a subunit of oligosaccharyltransferase in the endoplasmatic reticulum and catalyzes N-glycosylation of membrane and secretory proteins. The aim of the study was to identify target genes for TUSC3 in human colorectal cancer cells. We used microarrays to rev...
ORGANISM(S): Homo sapiens 
2017-07-21 | GSE93964 | GEO
ProteomicsResponse Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action - cytoplasmic proteins of KP46-treated HCT 116 epithelial cells
Response profiling using shotgun proteomics for establishing global metallodrug mechanisms of action in two colon carcinoma cell lines, HCT116 and SW480, was applied and evaluated with the clinically approved arsenic trioxide. Surprisingly, the complete established mechanism of action of arsenic tr...
ORGANISM(S): Homo sapiens (Human) 
2022-02-24 | PXD004765 | Pride
Metallodrug Proteome profiling Mechanism of action Functional protein groups Response profiling 
UnknownEffector protein Hcp2a of avian pathogenic Escherichia coli interacts with the endoplasmatic reticulum associated RPL23 protein of chicken DF-1 fibroblasts.
Not available
S-EPMC9885592 | biostudies-literature
UnknownMolecularly distinct routes of mitochondrial Ca2+ uptake are activated depending on the activity of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA).
Not available
S-EPMC3663555 | biostudies-literature
UnknownNADPH oxidase-dependent production of reactive oxygen species induces endoplasmatic reticulum stress in neutrophil-like HL60 cells.
Not available
S-EPMC4323339 | biostudies-literature
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