Sort   by:  
 Page size 
ProteomicsPTPN23-dependent ESCRT machinery functions as a cell death checkpoint in restraining multiple cell death pathways
In our study, a CRISPR screen of acute myeloid leukemia cells identifies protein tyrosine phosphatase non-receptor type 23 (PTPN23) as essential for survival. Loss of PTPN23 activates nuclear factor-kappa B, apoptotic, necroptotic, and pyroptotic pathways by causing the accumulation of death recepto...
ORGANISM(S): Homo Sapiens 
2024-10-15 | PXD056836 |
GenomicsTranscriptome-wide view of endosomal mRNP transport [iCLIP ]
Transcriptome-wide view of endosomal mRNP transport [iCLIP ]
PRJNA431398 | ENA
GenomicsTranscriptome-wide view of endosomal mRNP transport [RNA-Seq]
Transcriptome-wide view of endosomal mRNP transport [RNA-Seq]
PRJNA431397 | ENA
ProteomicsUSP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
The endosomal system is a highly dynamic multifunctional organelle, whose complexity is regulated in part by reversible ubiquitylation. Despite the wide-ranging influence of ubiquitin in endosomal processes, relatively few enzymes utilizing ubiquitin have been described to control endosome integrity...
ORGANISM(S): Homo sapiens (Human) 
2019-03-20 | PXD011899 | Pride
Endosomal trafficking Ubiquitin specific protease Ubiquitin Usp32 Rab gtpase 
OtherTranscriptome-wide view of endosomal mRNP transport [iCLIP ]
Spatiotemporal protein expression is mediated by active transport and local translation of mRNAs. Key factors of the transport machinery are RNA-binding proteins (RBPs) that recognise mRNAs as cargo for motor-based transport. However, a global view of transported mRNAs with cognate RBP binding sites...
ORGANISM(S): Mycosarcoma maydis 
2018-12-10 | GSE109557 | GEO
GenomicsTranscriptome-wide view of endosomal mRNP transport
Transcriptome-wide view of endosomal mRNP transport
PRJNA431390 | ENA
OtherTranscriptome-wide view of endosomal mRNP transport [RNA-Seq]
Spatiotemporal protein expression is mediated by active transport and local translation of mRNAs. Key factors of the transport machinery are RNA-binding proteins (RBPs) that recognise mRNAs as cargo for motor-based transport. However, a global view of transported mRNAs with cognate RBP binding sites...
ORGANISM(S): Mycosarcoma maydis 
2018-12-10 | GSE109560 | GEO
ProteomicsTMEM16K is an interorganelle regulator of endosomal sorting.
Using proximity biotinylation proteomics based on TMEM16K/Ano10 (an endoplasmic reticulum lipid scramblase causative for spinocerebellar ataxia) BioID chimeras, we identify endosomal transport as a major functional cluster of interacting proteins.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-05-30 | PXD018990 | Pride
Bioid Endosomal sorting Tmem16k 
TranscriptomicsWnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis
The Wnt pathway, which controls crucial steps of the development and differentiation programs, has been proposed to influence lipid storage and homeostasis. In this paper, using an unbiased strategy based on high content genome-wide RNAi screens that monitored lipid distribution and amounts, we find...
ORGANISM(S): Homo sapiens 
2015-06-20 | E-MTAB-2872 | biostudies-arrayexpress
UnknownSystems mapping of bidirectional endosomal transport through the crowded cell.
Not available
S-EPMC11466077 | biostudies-literature
Sort   by:  
 Page size