Sort   by:  
 Page size 
GenomicsGenome-wide maps of chromatin state in E12.5 mouse forelimbs
The chromatin state in developing body parts provides a zip code to cellular populations that direct their cell fates. We used antibodies for H3K4me3, H3K27me3 and Pol2, to identify the chromatin state signature of the mouse forelimb during mid-gestation, at embryonic day 12. The families of genes m...
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-49010 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
GenomicsMapping the Chromatin State Dynamics in Myoblasts
The chromatin state in developing body parts provides a zip code to cellular populations that direct their cell fates. We used antibodies for H3K4me3, H3K27me3 and Pol2, to identify the chromatin state signature of the Pitx2-null mouse forelimb during mid-gestation, at embryonic day 12. The families...
ORGANISM(S): Mus musculus 
2016-07-17 | E-GEOD-71128 | biostudies-arrayexpress
TranscriptomicsRegulation of the core pre-mRNA splicing machinery by MYC and PRMT5 is essential to sustain lymphomagenesis [B-cells]
Over-expressed MYC binds to virtually all active promoters within a cell, although with different binding affinities, and modulates gene expression, both positively and negatively. Here, we show that during lymphomagenesis in Eµ-myc transgenic mice, MYC directly up-regulates the transcription of the...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-60188 | biostudies-arrayexpress
TranscriptomicsEffects of fescue toxicosis on rat hepatic tissue
Rats (n=24) were fed ad libitum diets containing either ground endophyte-free (E-) seed or endophyteâ??infected (E+) seed for five days at thermoneutrality (21°C). Rats (n=24) with intraperitonial transmitters were used with core temperature (Tc) and general activity measured every 5 minutes durin...
ORGANISM(S): Rattus norvegicus 
2010-06-10 | E-GEOD-2452 | biostudies-arrayexpress
TranscriptomicsMouse, pig, and human atherosclerotic lesions have common and distinct mesenchymal cell populations
The single-cell RNA-seq experiment aims to explore the cell-type composition of right coronary artery plaques to provide an overview of human-like atherosclerosis. The PCSK9 transgenic minipigs were subjected to 15 months of HFHC diet (HFHC group f, n=4; m, n=1). At the time of euthanasia, plaque pa...
ORGANISM(S): Sus scrofa 
2025-08-30 | E-MTAB-15464 | biostudies-arrayexpress
TranscriptomicsEarly disruption of maternal-zygotic interaction and activation of defense-like responses in Arabidopsis interspecific incompatibility
Hybridization of diverged taxa often result in lethality or sterility. We previously described natural variation for postzygotic incompatibility in the cross of diploid Arabidopsis thaliana to Arabidopsis arenosa. Hybrid seed death in this system has a complex genetic basis, involving many non-addit...
ORGANISM(S): Arabidopsis thaliana 
2013-06-05 | E-GEOD-42957 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of transcriptome dynamics during growth in Angus cattle longissimus muscle
The bovine transcriptome dynamics in logissimus muscle (LM) during the post-natal growth remain unknown. Biopsies of LM from Angus steers were harvested at 0, 60, 120, and 220 d from early-weaning. A 13,153 bovine oligonucleotide array was used for transcript profiling. Functional analysis of microa...
ORGANISM(S): Bos taurus 
2013-06-21 | E-GEOD-48136 | biostudies-arrayexpress
GenomicsH3K27Ac and CENPA ChIP-seq experiments for the naked mole-rat liver
This data contributes to a telomere-to-telomere genome assembly and annotation of the naked mole-rat, Heterocephalus glaber. To epigenetically annotate centromeres, we performed CENPA ChIP-seq experiments in the male subordinate NMR livers. These experiments included an Input control, and a H3K27Ac ...
ORGANISM(S): Heterocephalus glaber 
2026-08-05 | E-MTAB-17296 | biostudies-arrayexpress
UnknownAncestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity.
Not available
S-EPMC6817522 | biostudies-literature
Sort   by:  
 Page size