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Unknownbovine liver glutamate dehydrogenase
Not available
EMPIAR-10217 | biostudies-other
GenomicsAuthentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
2016-09-09 | E-MTAB-4600 | biostudies-arrayexpress
ProteomicsA quantitative tissue-specific landscape of protein redox regulation during aging
Mammalian tissues engage in specialized physiology that is regulated by post-translational protein modification. A major mode of protein regulation is initiated by reactive oxygen species (ROS) that reversibly modify protein cysteine residues. ROS regulate a myriad of biological processes and ROS ...
ORGANISM(S): Mus musculus (Mouse) 
2020-02-27 | PXD017050 | Pride
Cpt Redox Aging Cysteine proteomics 
UnknownThermoplasma acidophilum 20S
Not available
EMPIAR-10218 | biostudies-other
ProteomicsArchitecture of the outbred brown fat proteome defines regulators of metabolic physiology
Obesity is a polygenic disorder with variable penetrance in the general population. Brown adipose tissue (BAT) is a major regulator of energy expenditure and metabolic physiology due to a specialized proteome that orchestrates futile metabolic cycles, which could be leveraged to treat obesity. Howev...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-08 | PXD036947 | Pride
Diversity outbred Qtl Physiology Metabolic disease Network Proteome Obesity Phenotype 
GenomicsChromatin and Transcriptional Signatures for Nodal Signaling During Endoderm Formation in hESCs
To elucidate the Nodal transcriptional network that governs endoderm formation, we used ChIP-Seq to identify genomic targets for SMAD2/3, SMAD3, SMAD4, FOXH1 and the active and repressive chromatin marks, H3K4me3 and H3K27me3, in human embryonic stem cells (hESCs) and derived endoderm. We demonstrat...
ORGANISM(S): Homo sapiens 
2011-05-21 | E-GEOD-29422 | biostudies-arrayexpress
TranscriptomicsWhole blood mRNA transcription profiling of host immune changes in neonatal sepsis during vancomycin therapy
The purpose of this study was to investigate changes in host gene expression profiles of neonatal infants with sepsis prior to the initiation of and during vancomycin therapy, to identify treatment-responsive genes and signature pathways associated with recovery from neonatal sepsis. The study analy...
ORGANISM(S): Homo sapiens 
2025-11-25 | E-MTAB-15687 | biostudies-arrayexpress
GenomicsRodent trophoblast epigenome
We characterized the trophoblast stem cell epigenome and gene expression profiles in rat and mouse. We profiled 5 histone modifications (+ chromatin input) using ChIP-Seq, and digital expression profiles (3' RNA-Seq) for trophoblast stem cells derived from rat and mouse. Furthermore, for mouse, we p...
ORGANISM(S): Mus musculus 
2012-12-04 | E-GEOD-42207 | biostudies-arrayexpress
TranscriptomicsDNA binding factors shape the mouse methylome at distal regulatory regions.
This SuperSeries is composed of the following subset Series: GSE30202: DNA binding factors shape the mouse methylome at distal regulatory regions [BIS_seq] GSE30203: DNA binding factors shape the mouse methylome at distal regulatory regions [ChIP-seq] GSE30204: DNA binding factors shape the mouse me...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-30206 | biostudies-arrayexpress
TranscriptomicsTrophoblast giant cell underrepresentation (tiling)
We profiled trophoblast stem cell replication-timing in order to compare these data to our data on underrepresented (UR) domainss in trophoblast giant cells (polyploid cells derived from 2N trophoblast stem cells). We found that UR domains are formed from late-replicating regions in tropoblast stem...
ORGANISM(S): Mus musculus 
2014-05-29 | E-GEOD-50207 | biostudies-arrayexpress
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