Sort   by:  
 Page size 
GenomicsTranscription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites [S-phase/M-phase synchronized cells]
During cell division, transcription factors (TFs) are removed from chromatin twice, during DNA synthesis, and during condensation of chromosomes. How TFs can efficiently find their sites following these stages has been unclear. Here, we have analyzed the binding pattern of expressed TFs in human col...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-51290 | biostudies-arrayexpress
GenomicsTranscription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites
During cell division, transcription factors (TFs) are removed from chromatin twice, during DNA synthesis, and during condensation of chromosomes. How TFs can efficiently find their sites following these stages has been unclear. Here, we have analyzed the binding pattern of expressed TFs in human col...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-49402 | biostudies-arrayexpress
TranscriptomicsEffect of Integrin-aBb2 on transcription in 2d or 3d.
M21 or M21L cells were grown either in 2d (on plastic) or in a 3d-collagen model. 2x2 design, in triplicate
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-34219 | biostudies-arrayexpress
GenomicsTranscription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites [Validation Set]
During cell division, transcription factors (TFs) are removed from chromatin twice, during DNA synthesis, and during condensation of chromosomes. How TFs can efficiently find their sites following these stages has been unclear. Here, we have analyzed the binding pattern of expressed TFs in human col...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-51142 | biostudies-arrayexpress
GenomicsTranscription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites [GP5d/siRAD21 ChIP-Seq experiments]
During cell division, transcription factors (TFs) are removed from chromatin twice, during DNA synthesis, and during condensation of chromosomes. How TFs can efficiently find their sites following these stages has been unclear. Here, we have analyzed the binding pattern of expressed TFs in human col...
ORGANISM(S): Homo sapiens 
2013-09-28 | E-GEOD-51234 | biostudies-arrayexpress
TranscriptomicsEffect of wtp53-reactivating drug RITA on HCT116 cells
Since its discovery as a tumour suppressor some fifteen years ago, the transcription factor p53 has attracted paramount attention for its role as “the guardian of the genome”. TP53 mutations occur so frequently in cancer, regardless of patient age or tumour type, that they appear to be part of the l...
ORGANISM(S): Homo sapiens 
2009-02-28 | E-GEOD-11578 | biostudies-arrayexpress
TranscriptomicsA survey of human brain transcriptome diversity at the single cell level
We used single cell RNA sequencing on 466 cells to capture the cellular complexity of the adult and fetal human brain at a whole transcriptome level. Healthy adult temporal lobe tissue was obtained from epileptic patients during temporal lobectomy for medically refractory seizures. We were able to c...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-67835 | biostudies-arrayexpress
TranscriptomicsExpression data from LoVo and GP5d CRC cell lines
TF binding clusters in promoter correlate well with gene expression. We used ChIP-seq to map binding sites of the majority of highly expressed TFs in the cell. The size of clusters of TFs in the promoters of genes were found to correlate well with gene expression. CRC cell lines were grown on plasti...
ORGANISM(S): Homo sapiens 
2013-08-16 | E-GEOD-48448 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Drosophila melanogaster to count absolute number of molecules using unique molecular identifiers
Drosophila melanogaster mRNA sequencing using unique molecular identifiers (umis).
ORGANISM(S): Drosophila melanogaster 
2011-11-21 | E-MTAB-816 | biostudies-arrayexpress
TranscriptomicsMulti-modal single-cell sequencing of differentiating mESCs using Smart-seq3 and scATAC-seq
We report dynamics of X-chromosome upregulation (XCU) along X-chromosome inactivation (XCI) in mESCs as they differentiate into EpiSCs. F1 hybrid C57BL6/J × CAST/EiJ male and female mESCs were grown in serum/LIF conditions were differentiated using Fgf2 and Activin A for 1, 2, 4 and 7 days to induce...
ORGANISM(S): Mus musculus 
2022-02-14 | E-MTAB-10714 | biostudies-arrayexpress
Sort   by:  
 Page size