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MetabolomicsThe HuMet Repository: Watching human metabolism at work
Metabolism oscillates between catabolic and anabolic states depending on food intake, exercise, or stresses that change a multitude of metabolic pathways simultaneously. We present the HuMet Repository for exploring dynamic metabolic responses to oral glucose/lipid loads, mixed meals, 36-h fasting, ...
2024-07-23 | MTBLS89 | MetaboLights
TranscriptomicsExpression Profile of Primary Colorectal Cancers and associated Liver Metastases
Comparison of expression profiles of primary colorectal cancers with liver metastases of the same patient. Additionally, expression data of normal colon and liver tissue. Abstract of publication will be included upon publication Keywords: expression profiling, colorectal cancer, colon cancer, liver...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-14297 | biostudies-arrayexpress
TranscriptomicsCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
The activation of the transcription factor NF-E2-related factor 2 (Nrf2) maintains cellular homeostasis in response to oxidative stress by the regulation of multiple cytoprotective genes. Without stressors the activity of Nrf2 is inhibited by its interaction with the kelch-like ECH-associated protei...
ORGANISM(S): Mus musculus 
2015-10-31 | E-GEOD-71695 | biostudies-arrayexpress
UnknownDietary fat and gut microbiota interactions determine diet-induced obesity in mice.
Not available
S-EPMC5123202 | biostudies-literature
UnknownDeterminants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naive healthcare workers.
Not available
S-EPMC8752368 | biostudies-literature
TranscriptomicsGenomic Profile of Primary Colorectal Cancers and associated Liver Metastases
Comparison of genomic alterations of primary colorectal cancers with liver metastases of the same patient Keywords: array CGH, colorectal cancer, colon cancer, liver metastasis 21 primary colorectal cancers and 21 matched liver metastases hybridized against sex-matched control pools
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-10179 | biostudies-arrayexpress
GenomicsDrugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
Oncogenic fusion events have been identified in a broad range of tumors. Among them, RET rearrangements represent distinct and potentially druggable targets that are recurrently found in lung adenocarcinomas. We provide further evidence that current anti-RET drugs may not be potent enough to induce ...
EGAS00001002335 | EGA
TranscriptomicsRat model of MTLE: Animals with epilepsy vs animals without epilepsy (codelink)
Neither the molecular basis of the pathologic tendency of neuronal circuits to generate spontaneous seizures (epileptogenicity) nor anti-epileptogenic mechanisms that maintain a seizure-free state are well understood. Here, we performed transcriptomic analysis in the intrahippocampal kainate model o...
ORGANISM(S): Rattus norvegicus 
2011-02-13 | E-GEOD-27166 | biostudies-arrayexpress
TranscriptomicsRat model of MTLE: Animals with epilepsy vs animals without epilepsy (Agilent)
Neither the molecular basis of the pathologic tendency of neuronal circuits to generate spontaneous seizures (epileptogenicity) nor anti-epileptogenic mechanisms that maintain a seizure-free state are well understood. Here, we performed transcriptomic analysis in the intrahippocampal kainate model o...
ORGANISM(S): Rattus norvegicus 
2011-02-13 | E-GEOD-27015 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-03-05-2017-12:40:06:735-476 - samples
RNAseq of LC2AD with AD80 or DMSO Plenker et al., Mechanistic insight into RET kinase inhibitors targeting the DFG-out conformation in RET-rearranged cancer
EGAD00001003316 | EGA
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