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ProteomicsSecretome and Proteome of WT and CFTR-KO pancreatic duct epithelial cells
Loss of CFTR function in the pancreatic duct leads to dysregulated luminal pH causing premature activation of digestive enzymes and tissue necrosis. Drastic alterations in pancreatic tissue architecture and cellular composition changes the microenvironment of the islets. Given that CFTR is expressed...
ORGANISM(S): Mustela putorius furo (European domestic ferret) (Mustela furo) 
2021-05-27 | PXD025126 | Pride
Pancreas Cystic fibrosis Cystic fibrosis related diabetes Ductal cells Proteome Secretome 
UnknownHighly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus.
Not available
S-EPMC6374392 | biostudies-literature
UnknownIn utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.
Not available
S-EPMC6489481 | biostudies-literature
UnknownTransgenic ferret models define pulmonary ionocyte diversity and function.
Not available
S-EPMC10533402 | biostudies-literature
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