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To investigate the possible range of additional RNase P substrates in vivo a strand-specific, high-density microarray was used to analyze what RNA accumulates with a mutation in the catalytic RNA subunit of nuclear RNase P in Saccharomyces cerevisiae. A wide variety of noncoding RNAs were shown to a...
ORGANISM(S): Saccharomyces cerevisiae 
Expression data of BL2 Burkitt Lymphoma cell line (controls and samples treated with different B cell specific stimuli) BL2 cells were cultured in RPMI and stimulated with the respective agents (rhCD40L, rhIL21, rhBAFF, LPS and antiIgM F(ab) fragments) for indicated timepoints. Cells were harvested ...
ORGANISM(S): Homo sapiens 
Burkitt’s lymphoma (BL) is an aggressive B-cell neoplasm that is currently treated by intensive chemotherapy in combination with anti-CD20 antibodies. Because of their toxicity, current treatment regimens are often not suitable for elderly patients or for patients in developing countries where BL is...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080781 | MassIVE
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