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MetabolomicsEngineered Bacillus subtilis WB600/ZD reduces post-weaning diarrhea in piglets by modulating gut microbiota and aryl hydrocarbon receptor (AHR) signaling

Post-weaning diarrhea (PWD) causes significant economic losses to the pig farming industry. Our previous study demonstrated that the engineered Bacillus subtilis WB600/ZD (an engineered Bacillus subtilis strain expressing the antimicrobial defensin peptide from Zophobas atratus), alleviates intes...

2025-08-15 | MTBLS12862 | MetaboLights
TranscriptomicsExpression analysis of Salmonella typhimurium LT2 TA100 upon exposure to C60
Investigation of gene expression level changes in Salmonella typhimurium LT2 TA100 upon exposure to C60, compared to unexposed controls. The mutations engineered into this strain make it susceptile to mutagenic compounds. The Salmonella typhimurium TA100 strain used in this study is further describ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2012-09-01 | E-GEOD-35750 | biostudies-arrayexpress
TranscriptomicsModeling host-microbe interactions in immunocompetent engineered human gut tissues
This data provides a single-cell RNA-seq characterization of human intestinal engineered epithelium and its interaction with tissue-resident memory T cells (scRNA-seq) or the pathogen Salmonella Typhimurium (scRNA-seq and scATAC-seq).
ORGANISM(S): Homo sapiens 
2026-08-17 | E-MTAB-16821 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expression by putative aspartate racemases, YgeA and AspR, in Salmonella Typhimurium
Amino acid racemases are enzymes that catalyze the conversion between L and D- forms of amino acids. While the role of alanine and glutamate raemases in bacteria (specifically Salmonella) are well-studied, relatively less is known about the function of other non-canonical racemases. This study focus...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2015-08-31 | E-GEOD-62658 | biostudies-arrayexpress
ProteomicsTumor temporal proteome profiling reveals the immunological triple offensive induced by synthetic anti-cancer Salmonella
The engineered “obligate” anaerobic Salmonella typhimurium strain YB1 shows a prominent ability to repress tumor growth and metastasis, which has great potential as a novel cancer immunotherapy. However, the antitumor mechanism of YB1 remains unelucidated. To resolve the proteome dynamics induced by...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-13 | PXD026288 | Pride
Quantitative proteomics Tumor specific t cell Cancer immunotherapy Blood coagulation M1 macrophage Engineered salmonella 
TranscriptomicsChIP-chip analysis of CspC binding in Salmonella enterica serovar Typhimurium strain SL1344
We performed Chromatin Immunoprecipitation (ChIP) and microarray hybridization analysis of CspC binding in Salmonella Typhimurium strain SL1344 which has been genetically engineered to express a 3xFLAG tagged CspC protein. Chromatin samples were prepared from SL1344 CspC 3xFLAG grown to exponential ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2015-02-26 | E-GEOD-66288 | biostudies-arrayexpress
ProteomicsStructure of a contractile injection system in Salmonella enterica subsp. salamae
Extracellular contractile injection systems (eCISs) are phage-derived nanomachines used by bacteria to deliver effectors into target cells. Well-studied examples include the Photorhabdus asymbiotica virulence cassettes and the antifeeding prophage from Serratia entomophila, which have been engineere...
ORGANISM(S): Salmonella enterica subsp. salamae 
2026-03-06 | PXD063506 | Pride
TranscriptomicsGene expression analysis of Salmonella enterica serovar Typhimurium strain SL1344 swap
We performed transcriptome abundance analysis of Salmonella Typhimurium strain SL1344 swap which has been genetically engineered to express the hns open-reading frame from the stpA promoter and the stpA open reading frame from the hns promoter. This strain is designated SL1344(swap). Transcript abun...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2013-11-09 | E-GEOD-52235 | biostudies-arrayexpress
UnknownAccurate and sensitive detection of Salmonella in foods by engineered bacteriophages.
Not available
S-EPMC7567081 | biostudies-literature
UnknownEngineered Probiotic for the Inhibition of Salmonella via Tetrathionate-Induced Production of Microcin H47.
Not available
S-EPMC5766358 | biostudies-literature
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