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TranscriptomicsEpigenome analysis of primary MCL
Genome wide DNA methylation profiling of primary MCL. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Bisulphite converted DNA from the 132 samples were hybridised to the Illumina Infinium 27k Human Methylati...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-45253 | biostudies-arrayexpress
TranscriptomicsGene expression following epigenetic drug treatment
MCL cell lines were treated with aza and aza in combination with TSA. MCL cell lines were treated with aza and aza in combination with TSA. Gene expression following drug treatment was compared with untreated cells.
ORGANISM(S): Homo sapiens 
2013-01-31 | E-GEOD-22038 | biostudies-arrayexpress
Genomicsena-DATASET-Hospital Clinic Barcelona-21-07-2015-12:09:53:274-78 - samples
RNASeq sequencing. Each library was sequenced using TruSeq SBS Kit v3-HS, in paired-end mode with a read length of 2 × 76 bp. We generated more than 20 million paired-end reads for each sample in a fraction of a sequencing lane on HiSeq2000 (Illumina Inc.) following the manufacturer’s protoc...
EGAD00001001443 | EGA
GenomicsIntegrated Genomic Analysis of Chronic Lymphocytic Leukaemia
Chronic lymphocytic leukaemia (CLL) is a frequent and heterogeneous disease whose genetic alterations determining the clinicobiological behaviour are not fully understood. Here, we describe a comprehensive evaluation of the genomic landscape of 452 CLLs and 54 monoclonal B-lymphocytosis (MBL), a pre...
EGAS00001001306 | EGA
Genomicsena-DATASET-Hospital Clinic Barcelona-12-08-2015-11:33:40:243-146 - samples
Exome Sequencing. 3 μg of genomic DNA from each sample were sheared and used for the construction of a paired-end sequencing library as described in the paired-end sequencing sample preparation protocol provided by Illumina41. Enrichment of exonic sequences was then performed for each library usi...
EGAD00001001464 | EGA
Genomicsena-DATASET-Hospital Clinic Barcelona-13-08-2015-12:02:30:199-229 - samples
Whole Genome sequencing. 2 μg of genomic DNA from each sample was used for the construction of two short-insert paired-end sequencing libraries. Both types of libraries were sequenced in paired-end mode on Illumina GAIIx (2 × 151 bp) using Sequencing kit v4 or Illumina HiSeq2000 (2x101 bp) usi...
EGAD00001001466 | EGA
GenomicsCLL Genome
The Chronic Lymphocytic Leukemia (CLL) Genome Project aims to identify genetic alterations involved in the development and progression of the CLL, which are still unknown, with the objective of generating a comprehensive catalogue of genetic alterations in 500 independent tumours. The CLL Genome Pro...
EGAS00000000092 | EGA
GenomicsU219-array-CLL-EGAS00001001306
CLL Expression Array
EGAD00010000875 | EGA
GenomicsEGAS00000000092-ega-27092011 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000044 | EGA
GenomicsEGAS00000000092-ega-20110419 2 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000023 | EGA
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