Epigenetic remodeling

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Genomics (1997)
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Organisms

Homo sapiens (574)
Mus musculus (557)
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Danio rerio (6)
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Mass Spectrometry (57)
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Instrument Platform

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Nuclear Magnetic Resonance (NMR) - (1)
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Liquid Chromatography MS - negative - hilic (1)

Publication Date

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2021 (101)
2015 (75)
2019 (73)
2013 (72)
2018 (66)
2020 (54)
2016 (52)
2012 (49)
2014 (45)
2011 (36)
2017 (31)
2010 (13)
2009 (12)
2008 (10)
2007 (6)
2006 (4)

UNIPROT ID/AC

10090.ENSMUSP00000032399 (2)
10090.ENSMUSP00000097919 (2)
1433B_MOUSE (2)
1433E_MOUSE (2)
1433F_MOUSE (2)
1433G_MOUSE (2)
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5NTD_MOUSE (2)
6PGD_MOUSE (2)
6PGL_MOUSE (2)
A0A0G2JDV3_MOUSE (2)
A0A0R4J159_MOUSE (2)
A0A140LIF8_MOUSE (2)
A0A1W2P6N8_MOUSE (2)
A0A286YCX6_MOUSE (2)
A0A2I3BQ48_MOUSE (2)

CHEBI ID

CHEBI:15741 (2)
CHEBI:16015 (2)
CHEBI:30915 (2)
CHEBI:57947 (1)
CHEBI:50383 (1)
CHEBI:5548 (1)
CHEBI:57540 (1)
CHEBI:58223 (1)
CHEBI:73533 (1)
CHEBI:73532 (1)
CHEBI:75947 (1)
CHEBI:13705 (1)
CHEBI:53389 (1)
CHEBI:57427 (1)
CHEBI:57972 (1)
CHEBI:57926 (1)
CHEBI:16367 (1)
CHEBI:5738 (1)
CHEBI:176586 (1)
CHEBI:57305 (1)
CHEBI:167175 (1)
CHEBI:746917 (1)
CHEBI:167938 (1)
CHEBI:15361 (1)
CHEBI:24996 (1)
CHEBI:17835 (1)
CHEBI:16001 (1)
CHEBI:17665 (1)
CHEBI:10642 (1)
CHEBI:17797 (1)

Metabolite Name

L-Carnosine (2)
Fumaric acid (2)
Adenosine (2)
L-Isoleucine (2)
L-Leucine (2)
L-Methionine (2)
Propionyl-coa (1)
Dimethyl-glycine (1)
Nicotinamide mononucleotide (1)
Scyllo Inositol (1)
Phosphoenol-pyruvate (1)
D-Glycerate 2-phosphate (1)
3-Phospho-D-glyceroyl phosphate (1)
Deoxy-D-Glucose (1)
3-Hydroxy Butyrate (1)
Adenosine 5'-diphosphate (1)
GLUCOSE (1)
Hydroxy-proline (1)
Cyclic guanosine monophosphate (1)
Adenosine 5'-triphosphate (1)
P-Cresol sulfate ammonium salt (1)
H-Phe-Trp-OH (1)
Gamma-Glu-Phe (1)
H-His-Trp-OH (1)
Phe Asn (1)
Phe phe (1)
Phe Met (1)
L-alpha-Aspartyl-L-phenylalanine (1)
H-Glu(Leu-OH)-OH (1)
Leu Val (1)

First Public Date

2026 (353)
2025 (217)
2024 (132)
2023 (126)
2022 (109)
2021 (101)
2019 (71)
2020 (65)
2014 (65)
2018 (64)
2015 (35)
2017 (34)
2013 (24)
2016 (17)

Classification

protozoa (5)
bacteria (2)
viruses (1)

Modification

N6 (1)
N6-dimethyl-L-lysine (1)
Not available (1)

Study type

Transcription profiling by array (85)
ChIP-seq (44)
Methylation profiling by array (32)
RNA-seq of coding RNA (29)
Methylation profiling by high throughput sequencing (21)
RNA-seq of non coding RNA (9)
ChIP-chip by tiling array (7)
Other (5)
ChIP-chip by array (4)
ATAC-seq (3)
Cell line - High-throughput sequencing (2)
Bisulfite-seq (2)
Comparative genomic hybridization by array (2)
MNase-seq (1)
MeDIP-seq (1)
Transcription profiling by tiling array (1)
MicroRNA profiling by array (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2025 (250)
2022 (209)
2021 (198)
2023 (184)
2024 (146)
2019 (136)
2018 (127)
2015 (119)
2020 (115)
2016 (115)
2013 (106)
2014 (87)
2017 (81)
2012 (79)
2026 (69)
2011 (55)
2010 (38)
2009 (38)
2008 (25)
2007 (12)
2005 (5)
2003 (4)
2004 (3)
2006 (2)
2002 (2)
2001 (2)

Lab affiliation

School of Life Sciences, Tsinghua University, China (2)
Shanghai Jiao Tong University (2)
(1) Maisonneuve Rosemont Hospital Research Center, CIUSSS Est de l’Île de Montréal, Montreal, QC, Canada (2) Department of Medicine, University of Montreal, Montréal, QC, Canada (1)
1. Barts Cancer Institute, Queen Mary University of London; Charterhouse Square, London EC1M 6BQ, UK. 2. Instituto de Parasitología y Biomedicina “López-Neyra” (IPBLN-CSIC); E-18016 Granada, Spain. (1)
1. Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany 2. Research group Molecular Mechanisms of Inflammation, Max-Planck Institute of Biochemistry, Martinsried, Germany (1)
1. SaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005, Ciudad Real, Spain. 2. Biochemistry Section, Faculty of Science and Chemical Technologies, and Regional Centre for Biomedical Research (CRIB), University of Castilla-La Mancha, 13071, Ciudad Real, Spain. (1)
1Department of Urology, Emory University School of Medicine, Atlanta, GA, USA (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University of Munich (TUM) Gregor-Mendel-Strasse 4 85354 Freising Germany (1)
Baylor College of Medicine Houston, Texas (1)
Biological Mass Spectrometry Lab, Department of Translational Medicine (DiMeT), Center for Translational Research on Autoimmune & Allergic Diseases - CAAD, University of Piemonte Orientale, Novara, Italy (1)
Biomedical Center, LMU Munich Molecular Biology Großhaderner Strasse 9 82152 Planegg-Martinsried Phone: (089) 2180 75420 (1)
Biomolecular characterization unit, Center for Sustainable Resource Science, RIKEN (1)
Biotechnology of Horticultural Crops, Technical University of Munich (1)
CNIO (1)
Cell Plasticity and Epigenetic Remodeling (F190) Deutsches Krebsforschungszentrum Im Neuenheimer Feld 280 69120 Heidelberg (1)
Center for Molecular Imaging, Departments of Radiology and Surgery, The University of Michigan, BSRB A502, Ann Arbor, MI 48109, United States. (1)
Center for RNA Research, Institute for Basic Science, Seoul 08826, S. Korea School of Biological Sciences, Seoul National University, Seoul 08826, S. Korea (1)
Centre for Gene Regulation and Expression University of Dundee (1)
Chemistry Institute, LADETEC, Proteomics Laboratory, UFRJ, RJ, Brazil. (1)
Departement for Biomedical Research University of Bern Switzerland (1)
Department of Biochemistry and Microbiology University of Victoria, Canada (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Chemistry and Biochemistry, The University of Texas at Dallas (1)
Department of Chemistry and Chemical Biology, Barnett Institute of Chemical & Biological Analysis, Northeastern University, Boston, MA, United States (1)
Department of Laboratory Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden (1)
Department of Laboratory Medicine, University of California, San Francisco, USA (1)
Department of Pharmacology, University of Nevada, Reno School of Medicine (1)
Department of Urology, Emory University School of Medicine, Atlanta, GA, USA (1)
Dept of Internal Medicine, Morsani College of Medicine, University of South Florida (1)
Division of Cancer Epigenomics, German Cancer Research Center (DKFZ) (1)

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Epigenetic coordination of transcriptional and translational programs in hypoxia

Adaptation to cellular stresses entails an incompletely understood coordination of transcriptional and post-transcriptional gene regulation. Here, we quantified hypoxia-dependent transcriptomes, epigenomes and translatomes in T47D breast cancer cells and H9 human embryonic stem cells. This reveal...

2025-06-09 | MTBLS12086 | MetaboLights

Histone serotonylation promotes pancreatic cancer development via lipid metabolism remodeling

Neurotransmitter serotonin (5-hydroxytryptamine [5-HT]) has emerged to play parallel roles in both neurobiology and oncology. Apart from receptor-mediated signaling transduction pattern, serotonin can be covalently integrated into histone (the post-translational modification known as histone sero...

2025-06-13 | MTBLS12569 | MetaboLights

Disruption of Methionine Metabolism Drives Erythroid Cell Fate Reprogramming by Remodeling the H3K4me3 Landscape

Methionine cycle plays critical roles in cell fate determination by shaping epigenetic landscape, yet its function in human erythropoiesis remains undefined. Here, we show that disruption of methionine metabolism by compromising key enzyme adenosylhomocysteinase (AHCY) reshapes H3K4me3 landscape,...

2026-06-10 | MTBLS10469 | MetaboLights

Dynamics of epigenetic regulation of gene expression during Plasmodium falciparum life cycle

In order to study the role of chromatin remodeling in transcriptional regulation associated with the progression of the P. falciparum intraerythrocytic development cycle (IDC), we mapped the temporal pattern of chromosomal association with histone H3 and H4 modifications using chromatin-immunoprecip...

ORGANISM(S): Plasmodium falciparum

2013-03-02 | E-GEOD-39238 | biostudies-arrayexpress

Genome-wide remodeling of the epigenetic landscape during myogenic differentiation

We have examined changes in the chromatin landscape during muscle differentiation by mapping the genome-wide location of ten key histone marks and transcription factors in mouse myoblasts and terminally differentiated myotubes, providing an exceptionally rich dataset that has enabled discovery of ke...

ORGANISM(S): Mus musculus

2011-05-08 | E-GEOD-25308 | biostudies-arrayexpress

Chromatin Remodeling Inactivates Activity Genes and Regulates Neural Coding

Activity-dependent transcription influences neuronal connectivity, but the roles and mechanisms of inactivation of activity-dependent genes have remained poorly understood. Genome-wide analyses in the mouse cerebellum revealed that the nucleosome remodeling and deacetylase (NuRD) complex deposits th...

ORGANISM(S): Mus musculus

2016-07-18 | E-GEOD-83253 | biostudies-arrayexpress

Acetate enhances long-term memory in female mice by sex-, context-, and brain region–specific epigenetic and transcriptional remodeling

Metabolic control of chromatin and gene expression is emerging as a key mechanism influencing critical neuronal functions. Here, we found that the intermediary metabolite acetate enhanced long-term memory in female mice, and this was associated with epigenetic and transcriptional remodeling in the d...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2024-08-12 | MSV000095573 | MassIVE

Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

Cell fate decisions depend on the interplay between chromatin regulators and transcription factors. Here we show that activity of the Mi-2u Nucleosome Remodeling and Deacetylase (NuRD) complex is controlled by the Ikaros family of lymphoid-lineage determining proteins. Ikaros, an integral component ...

ORGANISM(S): Mus musculus

2011-11-13 | E-GEOD-32311 | biostudies-arrayexpress

Diet-induced chromatin remodeling in mice livers

The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally involved in gene regulation, and aberrant modifications to chromatin are a hallmark of many diseases. We show here that a high fat (HF) diet leads to substantial chromatin remodeling in the livers of C57B...

ORGANISM(S): Mus musculus

2014-07-17 | E-GEOD-55581 | biostudies-arrayexpress

Histone modification analysis in TGFbeta/TNFalpha treated A549 spheroid cultures

We studied the extent of chromatin remodeling in an in-vitro model of the epithelial-mesenchymal transition (EMT). EMT is induced in spheroid cultures (3D) using simultaneously two cytokines: TGFbeta and TNFalpha. The epithelial-mesenchymal transition (EMT) is a cellular de-differentiation process t...

ORGANISM(S): Homo sapiens

2013-09-12 | E-GEOD-42374 | biostudies-arrayexpress

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