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Metabolic regulation is central to the tumor suppressor function of p53. Here we report that propionyl-CoA metabolic remodeling and epigenetic changes underpin p53-mediated restraint of autoimmunity through regulatory T (Treg) cells. By analyzing the human patients with autoimmune diseases, we fo...

2026-02-06 | MTBLS13473 | MetaboLights
The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms that exists in both unicellular and multicellular stages, to examine the role of epigenetics in regulating multicellularity. While...
ORGANISM(S): Dictyostelium Discoideum Ax2 
2021-06-15 | PXD024225 | panorama
ChIP-Seq of epigenetics mutants of Arabidopsis thaliana
Illumina RNA-Seq of epigenetics mutants of Arabidopsis thaliana
Bisulfite sequencing of epigenetics mutants of Arabidopsis thaliana
Oxford Nanopore Technology Direct RNA Sequencing of epigenetics mutants
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