Epithelial-mesenchymal transition (emt)

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Unknown (9533)
Genomics (1667)
Transcriptomics (1609)
Proteomics (172)
Other (44)
Methylation profiling (21)
Metabolomics (9)
Models (8)
Clinical (2)

Organisms

Homo sapiens (1441)
Mus musculus (472)
Rattus norvegicus (24)
Canis lupus familiaris (16)
Gallus gallus (9)
synthetic construct (9)
Danio rerio (7)
Betapolyomavirus hominis (3)
JC polyomavirus (3)
Betapolyomavirus macacae (3)
human gammaherpesvirus 4 (3)
Human alphaherpesvirus 1 (3)
Murid gammaherpesvirus 4 (3)
Murid betaherpesvirus 1 (3)
Human betaherpesvirus 5 (3)
Human gammaherpesvirus 8 (3)
Human immunodeficiency virus 1 (3)
Hydra vulgaris (2)
Dromaius novaehollandiae (2)
Sus scrofa (2)
Drosophila melanogaster (2)
Cervus nippon (1)
Mus musculus domesticus (1)
Sparus aurata (1)
Human alphaherpesvirus 2 (1)
Merkel cell polyomavirus (1)
Xenopus tropicalis (1)
Mus (1)
Xenopus laevis (1)
Escherichia coli (1)

Organisms

Homo sapiens (938)
Mus musculus (289)
Rattus norvegicus (11)
Canis lupus familiaris (9)
Gallus gallus (8)
Danio rerio (5)
Drosophila melanogaster (2)
Homo sapiens/Mus musculus xenograft (1)
Xenopus tropicalis (1)
Xenopus laevis (1)
Mus (1)
Hydra vulgaris (1)
Sus scrofa (1)

Repository

ENA (1415)
geo (1261)
biostudies-arrayexpress (649)
pride (115)
iProX (26)
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EGA (15)
MetaboLights (8)
BioModels (7)
PanoramaPublic (3)
ExpressionAtlas (2)
GPMDB (2)
jPOST (2)
Cell Collective (1)
GNPS (1)

Tissue

Cell culture (62)
Epithelial cell (35)
Permanent cell line cell (13)
Lung (7)
Fibroblast (5)
Melanocyte (4)
HeLa cell (4)
Skin (4)
Stem cell (4)
Colon (3)
Blood platelet (2)
Kidney (2)
Embryo (2)
Hepatocyte (2)
Midbrain (1)
Temporal lobe (1)
Pancreatic stellate cell (1)
Epithelium of pancreatic duct (1)
Breast epithelial cell (1)
Colorectal cancer cell (1)
Pancreatic ductal adenocarcinoma cell (1)
Pancreatic ductal cell (1)
Retinal pigment epithelial cell (1)
Nasal mucosa (1)
Mammary gland (1)
Peritoneal dialysis fluid (1)
Breast cancer cell (1)
Kidney epithelial cell (1)
Epithelial cell of lung (1)
Primary cell (1)

Disease

Breast cancer (22)
Colon cancer (7)
Disease free (6)
Melanoma (3)
Adenocarcinoma (2)
Breast carcinoma (2)
Not Available (2)
Non-small cell lung carcinoma (2)
Brain glioblastoma multiforme (2)
Prostate adenocarcinoma (2)
Pancreatic ductal adenocarcinoma (2)
Cervix carcinoma (2)
Neuroendocrine tumor (1)
Tumor (1)
Endometrial cancer (1)
Invasive carcinoma (1)
Diverticulosis (1)
Colorectal adenocarcinoma (1)
Prostate cancer (1)
Prostate carcinoma (1)
Colorectal Cancer (1)
Colorectal cancer and triple negative breast cancer patients (TNBC) who shown overexpression of fascin1 in the diagnostic biopsy tissue. (1)
Colorectal Neoplasms (1)
Ampulla of Vater cancer (1)
Calcium oxalate nephrolithiasis (1)
Ciliopathy (1)
Carcinoma (1)
Lung squamous cell carcinoma (1)
Pancreatic ductal carcinoma (1)
Age related macular degeneration (1)

Technology Type

Mass Spectrometry (115)
Shotgun proteomics (69)
Bottom-up proteomics (18)
Affinity purification coupled with mass spectrometry proteomics (8)
Data-independent acquisition (8)
Data-dependent acquisition (7)
SWATH MS (6)
Gel-based experiment (5)
Mass spectrometry (3)
Mass spectrometry assay (3)
MSE (3)
Top-down proteomics (3)
NMR spectroscopy (2)
HDMSE (2)
SRM/MRM (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
DiaPASEF (1)
All-ion fragmentation (1)

Instrument Platform

Illumina HiSeq 2500 (13)
Illumina NovaSeq 6000 (13)
NextSeq 500 (12)
Q Exactive (7)
Illumina MiSeq (6)
Illumina HiSeq 4000 (5)
Illumina HiSeq 2000 (4)
Microcentrifuge (2)
NextSeq 2000 (2)
NextSeq 550 (2)
Q Exactive Plus (2)
Instrument (2)
NEXTflex Small-RNA Seq kit v3 (Perkin Elmer) & NEXTflex Rapid XP DNA-seq kit v2 (Perkin Elmer) (1)
Direct-zol RNA microprep kit (Zymo Research), LabChip RNA pico sensitivity assay, Perkin Elmer & Nucleospin RNA kit (Macherey Nagel) (1)
PALM type 4 microscope (Zeiss) (1)
Linux server (GPU/CPU cluster) (1)
Biological safety cabinet, centrifuge, 40 µm strainer (1)
Standard cell culture setup (1)
Cell culture incubator (37 °C, 5 % CO₂) (1)
Element AVITI (1)
Fluidics station (1)
IScan Illumina (1)
QIAcube (Qiagen) (1)
EpMotion 5075 automated pipetting system (Eppendorf, Hamburg, Germany) (1)
Affymetrix GeneChip Scanner 3000 (1)
ScanArray Lite [PerkinElmer] (1)
Axon- GenePix4000B (1)
Illumina Genome Analyzer II (1)
Ion Torrent Proton (1)
DNBSEQ-G400 (1)

Publication Date

2026 (213)
2025 (198)
2022 (153)
2013 (142)
2023 (140)
2014 (140)
2016 (134)
2015 (110)
2012 (110)
2024 (108)
2021 (95)
2020 (93)
2011 (93)
2019 (92)
2018 (71)
2017 (69)
2010 (61)
2009 (37)
2008 (23)
2006 (6)
2007 (4)
2004 (2)
2005 (1)

UNIPROT ID/AC

O60716 (1)
P12830 (1)
O60315 (1)
P37275 (1)
O43623 (1)
O95863 (1)
Q9UJU2 (1)
P15884 (1)
Q06330 (1)
Q16665 (1)
P45984 (1)
Q04206 (1)
P35222 (1)
O60674 (1)
P61224 (1)
P62834 (1)
Q9GZV5 (1)
P46937 (1)
P46531 (1)
Q9NRM7 (1)
O95835 (1)
Q6V0I7 (1)
P49674 (1)
O14641 (1)
P31751 (1)
Q13418 (1)
P01112 (1)
Q05397 (1)
P08581 (1)
P56704 (1)

CHEBI ID

CHEBI:15760 (2)
CHEBI:27570 (2)
CHEBI:17895 (2)
CHEBI:17295 (2)
CHEBI:15354 (2)
CHEBI:16919 (2)
CHEBI:15428 (2)
CHEBI:7916 (2)
CHEBI:16958 (2)
CHEBI:18237 (2)
CHEBI:61293 (1)
CHEBI:74374 (1)
CHEBI:74231 (1)
CHEBI:75200 (1)
CHEBI:74465 (1)
CHEBI:74375 (1)
CHEBI:72065 (1)
CHEBI:72058 (1)
CHEBI:74371 (1)
CHEBI:74241 (1)
CHEBI:71727 (1)
CHEBI:145573 (1)
CHEBI:5738 (1)
CHEBI:180628 (1)
CHEBI:180627 (1)
CHEBI:180626 (1)
CHEBI:180625 (1)
CHEBI:180624 (1)
CHEBI:86090 (1)
CHEBI:90693 (1)

Metabolite Name

Tyramine (3)
LPE(18:0/0:0) (2)
Hypoxanthine (2)
Creatine (2)
Adenine (2)
L-Tyrosine (2)
L-Tryptophan (2)
Glycine (2)
Adenosine (2)
Xanthine (2)
Inosine (2)
Uridine (2)
5-(2-Azaniumylethyl)-2-hydroxyphenyl sulfate (1)
Carboxymethanesulfinyl-acetic acid (1)
4'-Chloroacetoacetanilide (1)
Tetralithium 3-hydroxy-3-methyl-5-{[(phosphonatooxy)phosphinato]oxy}pentanoate (1)
Estra-1,3,5(10)-triene-3,16alpha-diol, dipropionate (1)
Dinitrostilbenedisulfonic acid (1)
2-Chlorooxirane (1)
7-bromo-3,3a,6,8b-tetramethyl-2,3-dihydro-1H-cyclopenta[b]benzofuran (1)
Adenophostin a (1)
8-bromo-cGMP (1)
2,4,7,8,9-Pentachloro-3-dibenzofuranol (1)
6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one (1)
3-dehydro-L-gulonic acid 6-phosphate (1)
(2E)-but-2-ene-1,2,3-tricarboxylic acid (1)
(2E,4Z)-2-hydroxymuconic acid (1)
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate (1)
L-3-sulfolactaldehyde (1)
5-(4-Acetoxybut-1-ynyl)-2,2'-bithiophene (1)

First Public Date

2026 (200)
2025 (194)
2014 (165)
2023 (134)
2022 (122)
2024 (119)
2021 (88)
2020 (84)
2019 (82)
2017 (59)
2015 (56)
2018 (51)
2016 (42)
2013 (19)

Modelling Approach

Boolean model (3)
Logical model (3)
Ordinary differential equation model (1)

Study status

Ongoing (1)
Not provided (1)

Lab affiliation

Department of Biochemistry and Molecular Biology & The Center for Systems Biology University of Iceland Sturlugata 8, 101 Reykjavik Iceland. (3)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (3)
Shanghai Institute of Materia Medica, Chinese Academy of Sciences (2)
1. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht, 3584 CH, The Netherlands 2. Netherlands Proteomics Center, Padualaan 8, Utrecht, 3584 CH, The Netherlands (2)
Karolinska Institutet, Stockholm, Sweden (2)
Medical Proteomics Unit, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand (2)
University of Texas Medical Branch (2)
Institute of Medical Psychology LMU Munich Goethestrasse 31 80336 Munich (1)
1Research Institute of the McGill University Health Centre, Montreal, QC, Canada 2Department of Pathology, McGill University, Montreal, QC, Canada 3Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, Canada (1)
Reader,Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queens University Belfast (1)
Mayo Clinic, Rochester, MN (1)
Institute of Molecular Biology and Tumor Research (IMT)Philipps University of Marburg, Marburg, 35043, Germany and Department of Hematology, Oncology, and Immunology, University Hospital Giessen and Marburg, Marburg, 35043, Germany (1)
PRISM Lab U1192 (1)
School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China (1)
Institute of Translational Medicine and New Drug Development, Research Center for Cancer Biology, China Medical University (1)
Molecular Signaling group, Institute of biochemistry 2, Goethe University - Medical Faculty, Frankfurt am Main, Germany (1)
Department of Molecular Biolgy, Princeton University, USA (1)
Stem Cell and Developmental Biology, Laboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Bruxelles, Belgium (1)
Baker Heart and Diabetes Inst. (1)
School of Pharmacy, Lanzhou University, Lanzhou 730000, China (1)
1Department of Ophthalmology, Stem Cell Ocular Regenerative Medicine Center, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. (1)
MINT UMR Inserm 1066 CNRS 6021 IBS IRIS CHU 4 rue Larrey F-49933 ANGERS France (1)
Department of Chemistry & Biochemistry, University of Maryland, College Park, MD 20742 (1)
The Shraga Segal Department of Microbiology, Immunology and Genetics,National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, P.O.B. 653, Be'er-Sheva 84105, Israel (1)
Department of Pathology, Johns Hopkins Medical School, USA (1)
School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki (1)
Precision Medicine Research Center, School of Pharmacy, Binzhou Medical University, Yantai, Shandong Province, 264003, PR China (1)
Associate Professor Tracy Putoczki The Walter and Eliza Hall Institute of Medical Research Australia (1)
Institute for the Animal Production System in the Mediterranean Environment, National Research Council, 80055 Portici (Naples), Italy (1)
Genomics Research Center, Academia Sinica, Taipei, Taiwan. Drug Development Center, China Medical University, Taichung, Taiwan. Department of Biological Chemistry, University of California, Irvine. (1)

Keyword

Imipramine (1)
Epithelial to Mesenchymal Transition (1)
EMT (1)
EMT-TF (1)
MRNA (1)
Biomarkers (1)
Liquid biopsy (1)
Diagnosis (1)
CRC (1)

IsPrivate

False (7)

Modification

6x(2)H labeled dimethylated L-arginine (1)

Study type

Transcription profiling by array (450)
RNA-seq of coding RNA (77)
ChIP-seq (35)
Methylation profiling by array (14)
Other (8)
Comparative genomic hybridization by array (7)
RNA-seq of coding RNA from single cells (6)
RNA-seq of total RNA (6)
ChIP-chip by tiling array (5)
Methylation profiling by high throughput sequencing (5)
Cell line - High-throughput sequencing (4)
DNA-seq (4)
RNA-seq of non coding RNA (4)
ChIP-chip by array (3)
Transcription profiling by RT-PCR (3)
MicroRNA profiling by array (3)
Unknown experiment type (2)
Genotyping by array (2)
CLIP-seq (2)
MicroRNA profiling by high throughput sequencing (2)
ChIP-chip by SNP array (1)
Transcription profiling by tiling array (1)
ATAC-seq (1)
Single nucleus RNA sequencing (1)
Proteomic profiling by array (1)
CUT&RUN (1)
Observational (1)
Interventional (1)

Release Date

2021 (1163)
2022 (1119)
2020 (927)
2023 (878)
2025 (862)
2019 (776)
2024 (721)
2016 (617)
2018 (600)
2017 (591)
2015 (453)
2014 (389)
2013 (284)
2012 (221)
2011 (172)
2010 (126)
2026 (120)
2009 (73)
2008 (44)
2007 (23)
2006 (8)
2004 (5)
2005 (4)
2003 (1)
2002 (1)
2001 (1)
1997 (1)

Location

Spain (1)
Italy (1)

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Single-cell lipidomic analysis of the Epithelial-Mesenchymal Transition (EMT) using MALDI-MSI

EMT is a metastasis-promoting process whose heterogeneity has been extensively studied at a gene expression level. EMT also involves reprogramming of lipid metabolism, however there has been little focus on heterogeneity on the lipid level. Here, we use MALDI-MSI to determine the levels of variou...

2026-04-15 | MTBLS12650 | MetaboLights

Gene expression profiling of NSCLC cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT)

Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features. In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mese...

ORGANISM(S): Homo sapiens

2014-11-19 | E-GEOD-49644 | biostudies-arrayexpress

EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer

The involvement of membrane-bound solute carriers (SLCs) in neoplastic transdifferentiation processes is poorly defined. Here, we examined changes in the SLC landscape during epithelial-mesenchymal transition (EMT) of pancreatic cancer cells. We show that two SLCs from the organic anion...

2021-10-15 | MTBLS1925 | MetaboLights

Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.

PeptideAtlas ID: PAe003680. Original data file: O070224-30.mgf. Data published as part of J Proteome Res. 2010 Feb 5;9(2):1007-19 . From the Abstract: {{i}}... To gain insights into extracellular mediators associated with EMT, we conducted an extensive proteomic analysis of the secretome from MDCK ...

ORGANISM(S): Dog, Canine_adenovirus, Canine_calicivirus, Canine_distemper_virus, Canine_minute_virus, Canine_oral_papillomavirus, Canine_papillomavirus_2, Canine_papillomavirus___3, Canine_papillomavirus___4, Canine_parvovirus

GPM11210000341 | GPMDB

An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.

Regulation of cell-cell junction formation and regulation of cell migration were enriched among EMT (Epithelial-Mesenchymal Transition)-associated alternatively splicing events. Our analysis suggested that most EMT-associated alternative splicing events are regulated by one or more members of the RB...

ORGANISM(S): Homo sapiens

2011-07-15 | E-GEOD-30290 | biostudies-arrayexpress

Histone modification analysis in TGFbeta/TNFalpha treated A549 spheroid cultures

We studied the extent of chromatin remodeling in an in-vitro model of the epithelial-mesenchymal transition (EMT). EMT is induced in spheroid cultures (3D) using simultaneously two cytokines: TGFbeta and TNFalpha. The epithelial-mesenchymal transition (EMT) is a cellular de-differentiation process t...

ORGANISM(S): Homo sapiens

2013-09-12 | E-GEOD-42374 | biostudies-arrayexpress

Epithelial-mesenchymal transition-associated miRNA signature between EMT(+) and EMT(-) samples in clear-cell renal cell carcinoma

By use of large-scale miRNA expression profiling we identified microRNAs with significantly different expressions in epithelial-mesenchymal transition (EMT)-positive tumors and selected microRNAs for training phase of the study to evaluate their diagnostic and prognostic potential. Further, microRNA...

ORGANISM(S): Homo sapiens

2016-08-01 | E-MTAB-4911 | biostudies-arrayexpress

Epithelial-mesenchymal transition-associated mRNA signature between EMT(+) and EMT(-) samples in clear-cell renal cell carcinoma

By use of large-scale mRNA expression profiling we identified mRNAs with significantly different expression in epithelial-mesenchymal transition (EMT)-positive tumors and selected mRNAs for training phase of the study to evaluate their diagnostic and prognostic potential. Further, mRNAs were forward...

ORGANISM(S): Homo sapiens

2016-08-01 | E-MTAB-4909 | biostudies-arrayexpress

SWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling

We previously identified a gene signature predicted to regulate the epithelial-mesenchymal transition (EMT) in both epithelial tissue stem cells and breast cancer cells. A phenotypic RNA interference (RNAi) screen identified the genes within this 140-gene signature that promoted the conversion of me...

ORGANISM(S): Homo sapiens

2013-08-19 | E-GEOD-40145 | biostudies-arrayexpress

Transcription profiling of mouse adult ovarian surface epithelial cells in epithelial to mesenchymal transition

Adult Ovarian Surface Epithelium (OSE) retains the ability to undergo Epithelial to Mesenchymal Transition (EMT). We established a cell culture of murine adult OSE in their epithelial state, and we induced EMT by modifying their culture conditions. In this experiment we compare the transcriptional p...

ORGANISM(S): Mus musculus

2010-03-02 | E-GEOD-19947 | biostudies-arrayexpress

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