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TranscriptomicsExpression data from human Ea.hy926 cells in response to epoxomicin and in dependency of TCF11 presence
Coordinated regulation of the ubiquitin-proteasome system is crucial for the cell to adjust its protein degradation capacity to changing proteolytic requirements. The transcription factor TCF11 has been identified as a regulator for 26S-proteasome formation in human cells to compensate for reduced ...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-22853 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human HEK293 cells treated with the proteasome inhibitor epoxomicin
The objective of this study is to identify the genes that are up-regulated amid proteasome dysfunction to facilitate the discovery of proteolytic pathways that are activated as a compensatory response to proteasome inhibition. Proteasome is a large multi-component proteolytic complex in the cell. It...
ORGANISM(S): Homo sapiens 
2009-01-27 | E-GEOD-14429 | biostudies-arrayexpress
UnknownFrom epoxomicin to carfilzomib: chemistry, biology, and medical outcomes.
Not available
S-EPMC3815659 | biostudies-literature
TranscriptomicsExpression data from human Ea.hy926 cells in response to epoxomicin and in dependency of TCF11 presence
Coordinated regulation of the ubiquitin-proteasome system is crucial for the cell to adjust its protein degradation capacity to changing proteolytic requirements. The transcription factor TCF11 has been identified as a regulator for 26S-proteasome formation in human cells to compensate for reduced p...
ORGANISM(S): Homo sapiens 
2010-10-08 | GSE22853 | GEO
UnknownPeptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptides.
Not available
S-EPMC3315381 | biostudies-literature
UnknownRegulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice.
Not available
S-EPMC4041039 | biostudies-literature
UnknownEpoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells.
Not available
S-EPMC9311580 | biostudies-literature
TranscriptomicsAlteration of gene expression profile in HEK293 cells treated with proteasome inhibitor epoxomicin
The objective of this study is to identify the genes that are up-regulated amid proteasome dysfunction to facilitate the discovery of proteolytic pathways that are activated as a compensatory response to proteasome inhibition. Proteasome is a large multi-component proteolytic complex in the cell. It...
ORGANISM(S): Homo sapiens 
2009-01-15 | GSE14429 | GEO
GenomicsHomo sapiens
Expression data from human Ea.hy926 cells in response to epoxomicin and in dependency of TCF11 presence
PRJNA128061 | ENA
UnknownSolid-Phase Synthesis and Application of a Clickable Version of Epoxomicin for Proteasome Activity Analysis.
Not available
S-EPMC9122039 | biostudies-literature
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