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GenomicsHydroxymethylation at gene regulatory regions directs stem cell commitment during erythropoiesis
CD34 positive hematopoietic stem cells were differentiated into erythroid lineage. Next generation sequencing (NGS) of 5hmC affinity pulldown and RNAseq were performed in four time point of different stages of erythroid differentiation. 4 RNA-Seq Samples (d0, d3, d7 and d10); 4 affinity-pulldown (d...
ORGANISM(S): Homo sapiens 
2014-03-28 | E-GEOD-40243 | biostudies-arrayexpress
TranscriptomicsTranscriptome and proteome analysis of tyrosine kinase treated canine mast cell tumour cells identifies potentially KIT signalling-dependent genes
Canine mast cell tumour proliferation depends to a large extent on the activity of KIT, a tyrosine kinase receptor. Inhibitors of the KIT tyrosine kinase have recently been introduced and successfully applied as a therapeutic agent for this tumour type. However, little is known on the downstream tar...
ORGANISM(S): Canis lupus familiaris 
2012-07-24 | E-GEOD-32657 | biostudies-arrayexpress
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