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ProteomicsEccrine sweat proteomics for the diagnosis of cystic fibrosis
In clinical routine, the diagnosis of cystic fibrosis (CF) is still a challenge due to the limitations of diagnosis guidelines and tests. A diagnosis test of choice, the sweat test measures eccrine sweat chloride concentration as a byproduct of the eccrine sweat gland CFTR function. Despite the comb...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD028518 | Pride
Human Orbitrap Biomarkers Eccrine sweat Cystic fibrosis Shotgun proteomics 
ProteomicsHuman eccrine sweat shotgun proteomics for personalized monitoring and therapy
The potential of eccrine sweat as a bio-fluid of interest for diagnosis and personalized therapy has not yet been fully evaluated, due to the lack of in-depth sweat characterization studies. Thanks to recent developments in the field of omics together with the availability of accredited eccrine swea...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025899 | Pride
Human Eccrine sweat Lc-ms/ms Shotgun proteomics 
ProteomicsExternal validation of serum biomarkers predicting short-term and mid/long-term relapse in Crohn’s disease patients stopping infliximab
Background and aims: In Crohn’s disease (CD) patients on combination therapy (infliximab and immunosuppressant) and stopping infliximab (STORI cohort), the risk of short-term (<6 months) and mid/long-term relapse (>6 months) was associated with specific blood protein profiles. Our aim was to test th...
ORGANISM(S): Homo Sapiens 
PXD051233 | panorama
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