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TranscriptomicsExpressionprofiling of a glnR-mutant of Mycobacterium tuberculosis during culture on nitrate
Identification of glnR-dependent regulation of nitrate assimilation Keywords: genetic modification Mycobacterium tuberculosis H37Rv wild type and glnR mutant strain were incubated in minimal medium supplemented with 5 mM NO3 for 18 and 48 hours. RNA was extracted at indicated time points and microa...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2010-06-20 | E-GEOD-13246 | biostudies-arrayexpress
Transcriptomicsaffy-agro-bi-medicago-AGRO-BI-Toulouse
affy_agro-bi_medicago - Identification of genes from the model legume Medicago truncatula whose expression is affected by the plant nitrogen status, with or without inoculation with the symbiotic bacteria Sinorhizobium meliloti. - Comparison of the supernodulant, nitrogen-insensitive, sunn-2 mutant ...
ORGANISM(S): Medicago truncatula 
2010-10-28 | E-GEOD-17253 | biostudies-arrayexpress
TranscriptomicsEpigenome analysis in HPV(-) and HPV(+) squamous cell carcinoma cell lines
Human papillomavirus (HPV)-associated head and neck cancers (HNSCCs) have a distinct risk profile and appreciate a prognostic advantage compared to HPV-negative HNSCC. Promoter hypermethylation has been widely recognized as an important mechanism in the progression of HNSCC, but the extent to which ...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-24087 | biostudies-arrayexpress
UnknownEfficacy of erdafitinib before or after enfortumab vedotin in FGFR3-altered advanced urothelial cancer: analysis of the UNITE collaborative study.
Not available
S-EPMC12605803 | biostudies-literature
UnknownTreatment-Related Adverse Events and Associated Outcomes in Patients With Advanced Urothelial Carcinoma Treated With Enfortumab Vedotin: Analysis of the UNITE Study.
Not available
S-EPMC12486332 | biostudies-literature
UnknownEnfortumab Vedotin Following Platinum Chemotherapy and Avelumab Maintenance in Patients with Metastatic Urothelial Carcinoma: A Retrospective Data from the ARON-2EV Study.
Not available
S-EPMC11557677 | biostudies-literature
TranscriptomicsTranscription profiling of yeast to investigate the involvement of Snf7 and Rim101 in regulation of TIR1 and anaerobically up-regulated genes
Despite the scientific and applied interest in anaerobic metabolism of Saccharomyces cerevisiae, not all genes whose transcription is up-regulated under anaerobic conditions have yet been linked to known transcription factors. Experiments with a reporter construct in which the promoter of the anaero...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-02 | E-GEOD-18128 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of diffuse pediatric low-grade gliomas identifies recurrent, oncogenic MYBL1-truncating rearrangements
Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but apart from BRAF mutations or duplications in specific subclasses, few genetic driver events are known. Diffuse PLGGs comprise a set of uncommon subtypes that exhibit invasive growth and are therefore especiall...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-45843 | biostudies-arrayexpress
TranscriptomicsHDAC Inhibitors induce tumor cell-selective pro-apoptotic transcriptional responses.
The identification of recurrent somatic mutations in genes encoding epigenetic enzymes, coupled with biochemical studies demonstrating aberrant recruitment of epigenetic enzymes such as histone deacetylases (HDACs) and histone methyltransferases (HMTs) to promoter regions through association with on...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-43010 | biostudies-arrayexpress
UnknownTailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
Not available
S-EPMC6193457 | biostudies-literature
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