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We used microarrays to detail the global programme of gene expression underlying palate development by persistent expression in R26Pax3 mice and identified distinct classes of up-regulated and down-regulated genes during this process. Experiment Overall Design: Palatal shelves were dissected at E14....
ORGANISM(S): Mus musculus 
Map the histone H3K9/14 acetylation regions of in human cells at 7 common fragile sites and their flanking non-fragile sequences as well as a 200kb containing the rare fragile site FRAXA, a 1,075kb non-fragile region on chr22, a hyperacetylated region HALPHA44, and a heterochromatic region HET405. T...
ORGANISM(S): Homo sapiens 
Tumor DNA was extracted from 100 bone marrow aspirate samples where CD138+ selection had been performed to enrich plasma cells from patients with multiple myeloma. Patient matched control DNA from either peripheral blood leukocytes or CD34+ stem cell harvests was also isolated. Both tumor and contro...
RNA from the same tumor sample (n=98) was also processed using the 3' IVT kit (Affymetrix) and hybridized to U133 Plus 2.0 arrays (Affymetrix).
Genomic abnormalities in MM are common and can affect a patients outcome. Here we have performed targeted sequencing on xx patient tumor samples and matched control DNA. The targeted panel consists of ~160 genes and copy number regions, as well as key regions of chromosomal translocation including ...
4 pan-Neisseria arrays examining the gonococcal response to iron availability. Dual channel (Cy3/Cy5) arrays, using random nonamers for cDNA generation. Arrays scanned with ScanArray ExpressHT microarray scanner. Data analyzed using ArrayVision 7.0 and compiled in GeneSpring.
ORGANISM(S): Neisseria gonorrhoeae 
Increasing evidence suggests that low-abundant transcripts may play fundamental roles in biological processes. In an attempt to estimate the prevalence of low-abundant transcripts in eukaryotic genomes, we performed a transcriptome analysis in Drosophila using the SAGE technique. We collected 244,31...
ORGANISM(S): Drosophila melanogaster 
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