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UnknownMessenger RNA sequence rather than protein sequence determines the level of self-synthesis and antigen presentation of the EBV-encoded antigen, EBNA1.
Not available
S-EPMC3531512 | biostudies-literature
UnknownHyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma.
Not available
S-EPMC6005364 | biostudies-literature
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 6 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33934 | biostudies-arrayexpress
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 5 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33932 | biostudies-arrayexpress
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 7 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33935 | biostudies-arrayexpress
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 4 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33928 | biostudies-arrayexpress
TranscriptomicsMechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis
Data from clinical studies, cell culture, and animal models implicate the urokinase (uPA)/Plasminogen (Plg) system in the development of atherosclerosis and aneurysms. However, the mechanisms through which uPA/Plg stimulate these diseases are not yet defined. We used genetically modified, atherosc...
ORGANISM(S): Mus musculus 
2011-05-03 | E-GEOD-29028 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in cartilage from the mouse DMM osteoarthritis model
Transcriptional profiling of mouse cartilage comparing destabilised medial meniscal operated knee joints to sham operated knee joints in both wild type C57Bl/6 and C57Bl/6 ADAMTS5Dcat mice at 1, 2 and 6 weeks post DMM surgery. The goal was to determine the differential gene expression with the onset...
ORGANISM(S): Mus musculus 
2013-04-11 | E-GEOD-45793 | biostudies-arrayexpress
TranscriptomicsProfiling microRNA expression in bovine alveolar macrophages using RNA-seq
In this study, we determined the miRNA expression profile of bovine alveolar macrophages, using next-generation sequencing strategy. On an Illumina HiSeq 2000 machine, we sequenced 8 miRNA libraries, prepared from small RNA fractions of alveolar macrophages isolated from 8 different healthy animals ...
ORGANISM(S): Bos taurus 
2013-09-09 | E-GEOD-41138 | biostudies-arrayexpress
TranscriptomicsDNA Methylation Changes in Whole Blood and CD16+ Neutrophils in Response to Chronic Folic Acid Supplementation in Women of Childbearing Age
Folate, a water-soluble vitamin, is a key source of one-carbon groups for DNA methylation, but studies of the DNA methylation response to supplemental folic acid yield inconsistent results. The aim of this study was to determine if DNA methylation patterns in the dominant white blood cell type, neu...
ORGANISM(S): Homo sapiens 
2014-11-21 | E-GEOD-63499 | biostudies-arrayexpress
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