Epstein-barr virus (ebv)

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Transcriptomics (3851)
Unknown (3029)
Genomics (720)
Proteomics (82)
Other (45)
Methylation profiling (13)
Metabolomics (4)
Clinical (3)
Genomic (2)
Multiomics (2)

Organisms

Homo sapiens (2060)
Mus musculus (973)
Rattus norvegicus (118)
Arabidopsis thaliana (86)
Drosophila melanogaster (61)
Saccharomyces cerevisiae (57)
Sus scrofa (36)
Danio rerio (36)
Bos taurus (35)
Gallus gallus (31)
Caenorhabditis elegans (23)
Zea mays (18)
Oryza sativa (18)
Streptococcus pneumoniae D39 (16)
Escherichia coli (13)
Macaca mulatta (13)
Canis lupus familiaris (13)
Oryza sativa Japonica Group (12)
Schizosaccharomyces pombe (9)
Oncorhynchus mykiss (9)
Medicago truncatula (8)
Salmo salar (8)
Ovis aries (8)
Staphylococcus aureus (7)
Carassius auratus (6)
Glycine max (6)
Colinus virginianus (5)
Equus caballus (5)
Mycobacterium tuberculosis H37Rv (5)
Boehmeria nivea (4)

Organisms

Homo sapiens (342)
Mus musculus (22)
human gammaherpesvirus 4 (19)
Callithrix jacchus (1)
Gallus gallus (1)
Canis lupus familiaris (1)

Repository

biostudies-arrayexpress (3730)
ENA (502)
geo (361)
EGA (51)
pride (34)
MassIVE (20)
jPOST (5)
iProX (4)
MetaboLights (4)
EVA (3)
dbGaP (2)
ExpressionAtlas (1)
PanoramaPublic (1)

Tissue

B cell (17)
Cell culture (10)
Blood (2)
B-lymphoblastoma cell (1)
Blood plasma (1)
Blood serum (1)
Brain (1)
Burkitt lymphoma cell (1)
Burkitt lymphoma cell line (1)
Cell suspension culture (1)
Cerebral cortex glial cell (1)
Early embryonic cell (1)
Embryo (1)
Epithelial cell (1)
Erythrocyte (1)
Fibroblast (1)
Lymph node (1)
Lymphocyte (1)
Lymphocyte of B lineage (1)
Nasopharyngeal epithelial cell (1)
Peripheral blood mononuclear cell (1)
Permanent cell line cell (1)
RAJI cell (1)
Spleen (1)
Thymus (1)

Disease

Normal (6)
Breast cancer (4)
Lymphoma (3)
Burkitt lymphoma (2)
Multiple sclerosis (2)
Testicular seminoma (1)
CLL (1)
Arrhythmias and right ventricular dysfunction (1)
GIP-dependent Cushing's syndrome (1)
HPV positive (1)
Osteosarcoma subtype fibroblastic (1)
High grade glioblastoma (1)
Cocaine addiction (1)
Primary effusion lymphoma (PEL) (1)
DNA damage (1)
Acute lymphocytic leukemia (1)
Anaplastic large cell lymphoma has DiseaseStaging II (1)
Extranodal NK/T-Cell Lymphoma derived cell line (1)
Uninfected (1)
Schizophrenia (1)
Primary tumor (1)
Leukemia (1)
Renal cell carcinoma (1)
Glioblastoma (1)
Prostate carcinoma (1)
Nodal peripheral T-cell Lymphoma (1)
Burkitt Lymphoma (1)
Epstein-Barr Virus Infections (1)
Lymphoma (1)
Acute leukemia (1)

Technology Type

Mass Spectrometry (34)
Shotgun proteomics (18)
Bottom-up proteomics (12)
Affinity purification coupled with mass spectrometry proteomics (3)
Data-dependent acquisition (3)
Illumina HiSeq 2000 (2)
Mass spectrometry (2)
Data-independent acquisition (2)
Gel-based experiment (2)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500, ILLUMINA (1)
HiSeq X Ten (1)
Illumina HiSeq 2000, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Immunopeptidomics (1)

Instrument Platform

Illumina NovaSeq 6000 (19)
Illumina HiSeq 2500 (16)
Illumina HiSeq 2000 (15)
Illumina HiSeq 1500 (9)
Illumina HiSeq 4000 (9)
NextSeq 500 (7)
Illumina Genome Analyzer II (2)
Illumina NovaSeq X (2)
Illumina MiSeq (2)
NextSeq 550 (2)
10X Genomics Single Cell, V3.1 (1)
Agilent 2100 Bioanalyzer, Applied Biosystems 7900HT Sequence Detection System, Illumina TruSeq Small RNA Sample Preparation Kit (1)
RNeasy mini Kit, Ribo-Zero Human/Mouse/Rat kit (1)
Agilent Surescan High Resolution DNA microarray Scanner (1)
Beckman Coulter MoFlo Astrios (1)
Agilent G2565CA microarray scanner (1)
Solexa 2G Genome Analyzer (1)
BD FACSAria III (1)
Illumina iScan (1)
Agilent 2100 Bioanalyzer (1)
Illumina Genome Analyzer IIx (1)
G2565BA DNA microarray scanner [Agilent] (1)
GenePix 4000B [Axon Instruments] (1)
TruSeq (Illumina, Novogene, Genomic Centre Cambridge, CB4 0FW, UK.) (1)
NanoDrop spectrophotometer and the Agilent 2100 Bioanalyzer (1)
Histopaque-1077,FACSAria Fusion Sorter,Flow Cytometer (1)
NextSeq 2000 (1)
DNBSEQ-G400 (1)
MinION (1)
MassARRAY iPLEX (1)

Publication Date

2015 (650)
2010 (595)
2013 (526)
2014 (437)
2011 (437)
2012 (415)
2008 (195)
2016 (173)
2009 (154)
2007 (90)
2026 (58)
2024 (55)
2021 (54)
2025 (52)
2022 (49)
2019 (38)
2017 (34)
2018 (33)
2020 (27)
2023 (26)
2006 (25)
2005 (21)
2004 (10)
2003 (6)
2002 (2)

CHEBI ID

CHEBI:18237 (2)
CHEBI:32816 (2)
CHEBI:21363 (1)
CHEBI:183109 (1)
CHEBI:60312 (1)
CHEBI:15694 (1)
CHEBI:15919 (1)
CHEBI:35766 (1)
CHEBI:46171 (1)
CHEBI:84814 (1)
CHEBI:73209 (1)
CHEBI:78266 (1)
CHEBI:78261 (1)
CHEBI:84829 (1)
CHEBI:28037 (1)
CHEBI:165872 (1)
CHEBI:83053 (1)
CHEBI:36315 (1)
CHEBI:45826 (1)
CHEBI:75062 (1)
CHEBI:84153 (1)
CHEBI:15350 (1)
CHEBI:73218 (1)
CHEBI:33511 (1)
CHEBI:45696 (1)
CHEBI:133469 (1)
CHEBI:78647 (1)
CHEBI:44673 (1)
CHEBI:84415 (1)
CHEBI:45441 (1)

Metabolite Name

Isoleucine (2)
2-Arachidonyl glycerol ether (1)
Ï«-Cyclodextrin (1)
N-Acetyl-Dl-glutamic acid (1)
PG 18:1_18:1 (1)
PC O-18:1_16:0 (1)
PE 18:0_22:6 (1)
LNAPE 22:4/N-18:0 (1)
PG 18:0_18:1 (1)
PE 18:1_22:6 (1)
PA 18:0_18:2 (1)
SM 8:1;2O/34:0 (1)
Beta-Nicotinamide mononucleotide (1)
LNAPE 16:0/N-20:0 (1)
PE 18:0_22:5 (1)
PE O-18:0_22:4 (1)
PE O-17:1_22:6 (1)
PC 16:0_20:5 (1)
PE-Cer 12:1;2O/22:0 (1)
PC O-18:0_22:6 (1)
PC 18:0_22:4 (1)
19(R)-Hydroxy prostaglandin F2Ï« (1)
PE O-18:0_20:4 (1)
6Ï«-Prostaglandin I1 (1)
Ï«-D-Glucose-1,6-bisphosphate (1)
N1-[4-(2-thienylthio)phenyl]-4-chlorobenzamide (1)
PG 16:0_18:1 (1)
13,14-dihydro-15-keto Prostaglandin D1 (1)
16-(Hexopyranosyloxy)-7-hydroxy-8,9-epoxypimaran-18-oic acid (1)
PC O-16:1_22:6 (1)

First Public Date

2025 (70)
2014 (68)
2024 (60)
2026 (51)
2017 (36)
2021 (35)
2023 (33)
2020 (29)
2019 (29)
2018 (28)
2022 (21)
2015 (16)
2013 (16)
2016 (10)

Classification

viruses (19)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study status

No longer available (1)
Terminated (1)
Recruiting (1)

Study type

Transcription profiling by array (2656)
RNA-seq of coding RNA (439)
Unknown experiment type (125)
RNA-seq of non coding RNA (92)
ChIP-seq (60)
Comparative genomic hybridization by array (59)
Other (54)
Methylation profiling by array (45)
ChIP-chip by tiling array (36)
Transcription profiling by SAGE (33)
Transcription profiling by RT-PCR (17)
Proteomic profiling by array (17)
Transcription profiling by tiling array (16)
Cell line - High-throughput sequencing (13)
Methylation profiling by high throughput sequencing (12)
Genotyping by array (10)
RNA-seq of coding RNA from single cells (5)
RNA-seq of total RNA (5)
Human - High-throughput sequencing (4)
ChIP-chip by array (4)
MicroRNA profiling by array (3)
Human - Single-cell sequencing (2)
High-throughput sequencing (2)
Human - One-color microarray (2)
RNAi profiling by array (2)
MicroRNA profiling by high throughput sequencing (2)
ATAC-seq (2)
DNA-seq (2)
ChIP-chip by SNP array (1)
Transcription profiling by MPSS (1)

Release Date

2015 (776)
2010 (648)
2013 (582)
2014 (526)
2012 (491)
2011 (491)
2022 (331)
2021 (292)
2025 (280)
2016 (280)
2023 (261)
2020 (254)
2008 (223)
2019 (217)
2024 (216)
2009 (197)
2018 (185)
2017 (183)
2007 (116)
2006 (43)
2005 (37)
2026 (35)
2004 (27)
2003 (21)
2001 (13)
2002 (11)
1999 (10)
2000 (8)
1998 (5)

Lab affiliation

Cambridge Institute for Medical Research, Hills Road, Cambridge, CB2 0XY (2)
1Department of Hematology, Xiangya Hospital, Central South University, Changsha 410080, China 2NHC Key Laboratory of Carcinogenesis, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha 410078, China (1)
Cambridge Institute for Medical Research, University of Cambridge (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY (1)
Cancer Research Institute, Xiangya Basic Medical College, Central South University, No. 110 Xiangya Road, Kaifu District, Changsha City, Hunan Province (1)
Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. (1)
Chair of Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer-Forum 5, D-85354, Freising, Germany Bavarian Center for Biomolecular Mass Spectrometry, Technical University of Munich, Gregor-Mendel-Strasse 4, D-85354, Freising, Germany (1)
Department of Biomedical sciences FSU College of Medicine (1)
Department of Human Genetics (1)
Department of Human Genetics University of Chicago (1)
Department of Human Genetics, University of Chicago, Chicago, Illinois, USA; Department of Medicine, University of Chicago, Chicago, Illinois, USA (1)
Department of Medicine II, Hematology/Oncology, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany (1)
Department of Microbiology and Molecular Genetics University of Pittsburgh (1)
Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University (1)
Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Tübingen, Germany (1)
Head Proteomics Group Leiden University Medical Center, Center for Proteomics and Metabolomics, The Netherlands (1)
Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallés, Barcelona, Spain. (1)
Institute for Research in Immunology and Cancer, Department of Chemistry, Université de Montréal, Montréal, Québec, Canada H3T 1J4 (1)
Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München (1)
Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland (1)
Paul J Lehner PhD FRCP FMed Sci FRS Sheila Joan Smith Professor of Immunology Wellcome Principal Fellow and Honorary Consultant University of Cambridge CITIID Cambridge Biomedical Campus Cambridge CB2 0AW (1)
Pediatric Infectious Diseases Molecular Genetics and Microbiology Stony Brook University Life Sciences Building, Rm. 158 Stony Brook, NY 11794-5222 U.S.A. (1)
Philips Institute for Oral Health Research, VCU School of Dentistry, Virginia Commonwealth University, Richmond, Virginia 23298, USA (1)
ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, B-9000 Ghent, Belgium (1)
Professor of Molecular Biology, University of Dundee (1)
Quantitative Biology Center (QBiC), University of Tübingen, Germany. (1)
School of Cellular and Molecular Medicine University of Bristol BS8 1TD UK (1)
School of Dentistry, Virginia Commonwealth University, Richmond, Virginia 23298 USA (1)
School of Life Sciences University of Sussex Brighton BN1 9QG UK (1)
School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom (lab head) (1)

Location

United States (2)
Australia (1)
United Kingdom (1)
Spain (1)
Italy (1)
Belgium (1)
Canada (1)
Austria (1)
France (1)

Keyword

Epstein-Barr Virus (EBV) (2)
Allogeneic, Off-The-Shelf T-cell Immunotherapy (2)
Brentuximab Vedotin (1)
Solid Organ Transplant (HCT) (1)
Hematopoietic Cell Transplant (SOT) (1)
Primary Immunodeficiency (PID) (1)
Acquired Immunodeficiency (AID) (1)
Epstein-Barr Virus-associated Lymphoma (1)
HIV/AIDS Lymphoma (1)
Rheumatoid Arthritis and Lymphoma (1)
Tumor Necrosis Factor (TNF)-alpha Inhibitors and Lymphoma (1)
Inflammatory Bowel Disease and Lymphoma (1)
Epstein-Barr Virus-specific Cytotoxic T lymphocyte (EBV-CTL) (1)
Epstein-Barr Virus+ associated Nasopharyngeal Carcinoma (EBV+ NPC) (1)
Epstein-Barr Virus+ associated Leiomyosarcoma (EBV+ LMS) (1)
Immunoconjugates (1)
Rituximab (1)
Epstein-Barr Virus (EBV)-associated Lymphoproliferative Disease (LPD) (1)
Cytotoxic T lymphocyte (CTL) (1)
Cancer After Transplant (1)
Kidney transplant (1)
Renal transplant (1)
Liver transplant (1)
Heart transplant (1)
Lung transplant (1)
Intestinal transplant (1)
Pancreas transplant (1)
Post-transplant Lymphoma (1)
Solid Organ Transplant (SOT) (1)
Bone Marrow Transplant Complications (1)

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Ceramide Promotes Lytic Reactivation of Epstein-Barr Virus in Gastric Carcinoma

Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...

2023-12-20 | MTBLS7649 | MetaboLights

Characterization Epstein-Barr Virus-Associated Encephalitis via Identification of Metabolomic Biomarkers

Objective: Fulminant Epstein-Barr Virus (EBV) infection may lead to fatal outcomes in patients with EBV-associated encephalitis (EBVAE). To investigate potential biomarkers in EBVAE, we utilized an untargeted metabolomic methodology to identify disease-associated biomarkers in patients ...

2026-03-23 | MTBLS14111 | MetaboLights

A metabolic dependency of EBV can be targeted to hinder B cell transformation

Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate cell proliferation and transformation, contributing to the propensity of the virus to drive immune dysregulation and lymphomagenesis. We found that the EBV protein EBNA2 initiates NAD de novo bios...

2024-04-29 | MTBLS2243 | MetaboLights

Proteomics of EBV-infected lytic and refractory cells

Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-22 | MSV000079993 | MassIVE

Gene expression profiling of age-related EBV-positive B-cell lymphoproliferative disorders uncovers alterations in characteristic oncogenetic pathways: possible implications for pathogenesis

Comprehensive gene expression profiles of Epstein-Barr virus (EBV)-associated B cell neoplasm (clinical samples + cell lines)

ORGANISM(S): Homo sapiens

2014-04-11 | E-MTAB-973 | biostudies-arrayexpress

Epstein–Barr virus (EBV) Rta-mediated cell cycle arrest enables permissive replication of EBV and Kaposi’s sarcoma-associated herpesvirus in 293 cells

Epstein-Barr virus (EBV) Rta is a latent-lytic molecular switch evolutionarily conserved in all gamma-herpesviruses. In previous studies, doxycycline-inducible Rta was shown to potently produce an irreversible G1 arrest followed by cellular senescence in 293 cells. Here, we demonstrate that in this ...

ORGANISM(S): Homo sapiens

2011-03-31 | E-GEOD-24587 | biostudies-arrayexpress

Epstein-Barr virus growth/latency III program alters cellular microRNA expression

The Epstein-Barr virus (EBV) is associated with lymphoid and epithelial cancers. Initial EBV infection alters lymphocyte gene expression, inducing cellular proliferation and differentiation as the virus transitions through consecutive latency transcription programs. Cellular microRNAs (miRNAs) are...

ORGANISM(S): Homo sapiens

2010-05-19 | E-GEOD-13056 | biostudies-arrayexpress

Genome-Wide Analysis of Host-Chromosome Binding Sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)

The Epstein-Barr Virus (EBV) Nuclear Antigen 1 (EBNA1) protein is required for the establishment of EBV latent infection in proliferating B-lymphocytes. EBNA1 is a multifunctional DNA-binding protein that stimulates DNA replication at the viral origin of plasmid replication (OriP), regulates transc...

ORGANISM(S): Homo sapiens

2011-07-16 | E-GEOD-30709 | biostudies-arrayexpress

OLFM4 is a direct target of the cGAS-STING pathway and acts as an extracellular inhibitor for the Hippo signaling in EBV-associated cancer

To investigate protein components of MVs in EBVaGC, we collected clinical tissue samples of 3 EBV+ and 3 EBV- gastric cancer patients, and isolated MVs from these samples. Then performed 4D-label free quantitative proteomics analysis for each isolated MVs. Raw files of 6 samples are included in subp...

ORGANISM(S): Homo Sapiens

2024-11-18 | PXD057977 |

Transcription profiling by array of human lymphocyte cells lines generated with EBNA3-knockout Epstein-Barr Viruses

Epstein-Barr virus (EBV) is able to drive the transformation of B-cells, resulting in the generation of lymphocyte cell lines (LCLs) in vitro. EBV nuclear proteins EBNA3A and EBNA3C are necessary for efficient transformation, while EBNA3B is dispensable. We describe a transcriptome analysis of LCLs ...

ORGANISM(S): Homo sapiens

2010-10-30 | E-MEXP-2768 | biostudies-arrayexpress

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