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TranscriptomicsA Pathobiological Role of the Insulin Receptor in CLL.
Purpose: The chromosomal deletion 11q affects biology and clinical outcome in CLL but del11q-deregulated genes remain incompletely characterized. Results: We have identified differential expression of the insulin receptor (INSR) in CLL, including high-level INSR expression in the majority of CLL wi...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-26526 | biostudies-arrayexpress
UnknownRandomized Phase II Study of Azacitidine Alone or in Combination With Lenalidomide or With Vorinostat in Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: North American Intergroup Study SWOG S1117.
Not available
S-EPMC5562170 | biostudies-literature
TranscriptomicsComparative genomic hybridization of human chronic lymphocytic leukemia CLL patients and subtypes of del13q14
Chronic lymphocytic leukemia (CLL) is a biologically heterogeneous illness with a variable clinical course. Loss of chromosomal material on chromosome 13 at cytoband 13q14 is the most frequent genetic abnormality in CLL, but the molecular aberrations underlying del13q14 in CLL remain incompletely...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9250 | biostudies-arrayexpress
TranscriptomicsNF1 inactivation in adult acute myelogenous leukemia
Purpose: This study was conducted to identify novel genes with importance to the biology of adult acute myelogenous leukemia (AML). Conclusions: NF1 null states are present in 7/95=7% of adult AML and delineate a disease subset that could be preferentially targeted by Ras or mTOR-directed therapeut...
ORGANISM(S): Homo sapiens 
2010-12-02 | E-GEOD-21107 | biostudies-arrayexpress
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