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TranscriptomicsExpression data of RNA isolated from C57/BL6 mouse aortic endothelial cells (MAECs)
Our goal is to study the contribution of endothelial, smooth muscle, and macrophage gene expression to early atherosclerosis using vessels from healthy, pre-lesioned, and lesioned mice. To accomplish this, we developed a method to isolate endothelial cells directly from the aorta and quantitate tran...
ORGANISM(S): Mus musculus 
2012-07-10 | E-GEOD-39264 | biostudies-arrayexpress
TranscriptomicsAorta profiling HMDP
Identify genes in the aorta whose expressions under genetic regulation in the Hybrid Mouse Diversity Panel (HMDP). The HDMP is comprised of classical inbred and recombinant inbred wild-type mice. The RMA values of genes were used for genome-wide association as described in Bennett et al. Genome Rese...
ORGANISM(S): Mus musculus 
2012-11-18 | E-GEOD-38120 | biostudies-arrayexpress
TranscriptomicsGene expression in macrophages derived form wild-type and Ndfst1-deficient mice before and after foam cell conversion
In order to examine the role of macrophage heparan sulfate proteoglycans in atherogenesis, we inactivated the biosynthetic gene N-acetylglucosamine N-deacetylase-N-sulfotransferase 1 (Ndst1) in macrophages. In order to determine the impact of altering Ndst1 expression, we crossbred mice bearing a co...
ORGANISM(S): Mus musculus 
2014-11-04 | E-GEOD-51009 | biostudies-arrayexpress
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