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MetabolomicsExploring the effect of estrogen on Candida albicans hyphal cell wall glycans and ergosterol synthesis
Increased levels of 17-β estradiol (E2) due to pregnancy in young women or to hormonal replacement therapy in postmenopausal women have long been associated with an increased risk of yeast infections. Nevertheless, the effect underlying the role of E2 in Candida albicans infections is not wel...
2025-09-11 | MTBLS5821 | MetaboLights
ProteomicstRNA-m1A Methylation Regulates the Infection of Magnaporthe oryzae by Supporting Ergosterol Biosynthesis
Ergosterols are essential components of fungal plasma membranes. Inhibitors targeting ergosterol biosynthesis (ERG) genes are critical for controlling fungal pathogens, including Magnaporthe oryzae, the fungus that causes rice blast. In this study we show that the Trm6/Trm61 complex catalyzes dynami...
ORGANISM(S): Pyricularia Oryzae 70-15 
PXD051352 |
TranscriptomicsMutation in Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Fluconazole Resistance
In the pathogenic yeast Candida albicans, the zinc cluster transcription factor Upc2p has been shown to regulate expression of ERG11 and other genes involved in ergosterol biosynthesis upon exposure to azole antifungals. ERG11 encodes lanosterol demethylase, the target enzyme of this antifungal cla...
ORGANISM(S): Candida albicans 
2008-11-04 | E-GEOD-11320 | biostudies-arrayexpress
GenomicsLimosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion
Limosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion
PRJNA836885 | ENA
TranscriptomicsTranscription profiling of vanillin tolerant Saccharomyces cerevisiae to investigate link with ergosterol contents
The vanillin tolerance Saccharomyces cerevisiae was screened and compared intracellular ergosterol levels with several laboratory yeast strains, to study potential relationship between ergosterol contents and vanillin tolerance. S. cerevisiae NBRC1950 was selected as a vanillin tolerant strain. It...
ORGANISM(S): Saccharomyces cerevisiae 
2009-07-04 | E-GEOD-13755 | biostudies-arrayexpress
TranscriptomicsLimosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion
Candida glabrata is a human-associated opportunistic fungal pathogen. It shares its niche with Lactobacillus spp. in the gastrointestinal and vaginal tract. In fact, Lactobacillus species are thought to competitively prevent Candida overgrowth. We investigated the molecular aspects of this antifunga...
ORGANISM(S): Nakaseomyces glabratus 
2023-02-08 | GSE202656 | GEO
TranscriptomicsInvolvement of ergosterol contents in the tolerance to vanillin in Saccharomyces cerevisiae
The vanillin tolerance Saccharomyces cerevisiae was screened and compared intracellular ergosterol levels with several laboratory yeast strains, to study potential relationship between ergosterol contents and vanillin tolerance. S. cerevisiae NBRC1950 was selected as a vanillin tolerant strain. Its ...
ORGANISM(S): Saccharomyces cerevisiae Schizosaccharomyces pombe 
2009-06-29 | GSE13755 | GEO
UnknownAspergillus oryzae accelerates the conversion of ergosterol to ergosterol peroxide by efficiently utilizing cholesterol.
Not available
S-EPMC9441601 | biostudies-literature
UnknownInsights into Ergosterol Peroxide's Trypanocidal Activity.
Not available
S-EPMC6770379 | biostudies-literature
UnknownAbnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles.
Not available
S-EPMC5776110 | biostudies-literature
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