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UnknownImproved Ribo-seq enables identification of cryptic translation events.
Not available
S-EPMC6152898 | biostudies-literature
TranscriptomicsTranscription profiling of human umbilical vein endothelial cells (HUVEC) treated with VEGF-A
Angiogenesis, the formation of new capillaries by sprouting from preexisting vessels, is mainly induced by VEGF-A. To identify genes which are induced by VEGF-A in endothelial cells, HUVEC were starved and induced by VEGF-A165 for 30, 60 and 150min. RNA of induced and uninduced cells was isolated an...
ORGANISM(S): Homo sapiens 
2009-10-20 | E-GEOD-15464 | biostudies-arrayexpress
TranscriptomicsNascent transcription defined by RNA polymerase IV in Zea mays
Maize RNA Polymerase D1 (RPD1), the largest subunit of RNA polymerase IV (Pol IV), is required for normal plant development, repression of transposable elements (TEs), and for the regulation of specific alleles associated with TEs. Here, we define the nascent transcriptomes of rpd1 mutant and wild-...
ORGANISM(S): Zea mays 
2015-02-04 | E-GEOD-54166 | biostudies-arrayexpress
Proteomics,Multiomicsp53-regulated networks of protein, mRNA, miRNA and lncRNA expression revealed by integrated pSILAC and NGS analyses
We determined the effect of p53 activation on de novo protein synthesis using quantitative proteomics of newly synthesized proteins (pulsed stable isotope labeling with amino acids in cell culture, pSILAC) in combination with mRNA and non-coding RNA expression analyses by next generation sequencing ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-05-24 | MSV000079767 | MassIVE
ProteomicsMHC-I peptidome analysis of human foreskin fibroblasts
Ribosome profiling (Ribo-seq) recently revealed the expression of thousands of short open reading frames (sORFs) in eukaryotic cells. They encode for a class of instable peptides, which evade experimental validation by whole-proteome mass spectrometry. Here, we show that computational elimination of...
ORGANISM(S): Homo sapiens (Human) 
2018-04-05 | PXD007203 | Pride
Human Hff Peptidome Mhc-i 
TranscriptomicsGenome-wide miRNA-expression analysis after p53 activation in colorectal cancer cells
In order to comprehensively identify miRNA-expression changes after p53-activation a miRNA-Seq analysis was conducted after activation of a conditional p53 allele in SW480 cells. SW480/pRTR-p53-VSV cells were subjected to miRNA-Seq analysis after 16 hours doxycycline-treatment. Kompetenzzentrum für ...
ORGANISM(S): Homo sapiens 
2015-07-21 | E-GEOD-67181 | biostudies-arrayexpress
TranscriptomicsWide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling
Primary human foreskin fibroblasts (HFF) were infected with wild-type simplex virus 1 (HSV-1) strain 17 at a multiplicity of infection (MOI) of 10. Ribosome profiling was performed at various times during infection with minor modification to the protocol described in Stern-Ginossar N et al., Science...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-60040 | biostudies-arrayexpress
UnknownNew and Interesting Fungi. 6.
Not available
S-EPMC10966675 | biostudies-literature
UnknownModel selection versus traditional hypothesis testing in circular statistics: a simulation study.
Not available
S-EPMC7327993 | biostudies-literature
UnknownCalcarides A-E, antibacterial macrocyclic and linear polyesters from a Calcarisporium strain.
Not available
S-EPMC3801122 | biostudies-literature
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