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Paraneoplastic pemphigus is an autoimmune mucocutaneous blistering disease. It is caused by an autoimmune reaction in patients with a malignant neoplasms. We here used proteome arrays to perform a comprehensive study of autoimmune targets in paraneoplastic pemphigus, anti-p200 pemphigoid (Ap200P), a...
ORGANISM(S): Homo sapiens 
Gene expression profiling of 23 grade II gliomas of different histological subtype. Analyses was done on 9 astrocytomas, 8 oligoastrocytomas and 6 oligodendrogliomas.
ORGANISM(S): Homo sapiens 
We examined tumours from a large cohort of patients with metastatic urothelial bladder cancer (mUC) treated with an anti–PD-L1 agent (atezolizumab) and identified major determinants of clinical response and immune escape. Whole transcriptome profiles were generated for 368 patients using TruSeq RNA ...
Tumor DNA was extracted from formalin-fixed and paraffin embedded tumors of a large cohort of bladder cancer patients before treatment with anti-PD-L1. Normal DNA was extracted from matched PBMCs. Whole exome sequencing was performed. This is a subset of patients for which RNA sequencing is also pro...
RNA was extracted from formalin-fixed and paraffin embedded tumors of a large cohort of bladder cancer patients before treatment with anti-PD-L1. RNA was sequenced using a capture based approach (exome capture, RNA access).
The immunopathological landscape of human pre-TCRα deficiency: from rare to common variants
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