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UnknownFecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity.
Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens. Here we report that sepsis in mice caused by a defined four-member pathogen community isolate...
S-EPMC7214422 | biostudies-literature
Genomicsena-DATASET-UCAM-GEL-15-04-2015-15:15:23:555-345 - samples
Whole exome sequencing BAM files for samples from the BRIDGE Consortium with pathogenic or likely pathogenic variants on genes linked to bleeding or platelet disorders.
EGAD00001001333 | EGA
GenomicsSequencing of heritable Bleeding and Platelet Disorders
The BRIDGE-BPD study aims to discover new causal genes for Bleeding and Platelet Disorders (BPD) by high throughput sequencing using cluster analyses based on improved and standardized deep phenotyping of cases. BPD is one of the 13 Rare Disease projects under the NIHR BioResource Rare Diseases BRID...
EGAS00001001172 | EGA
GenomicsNIHR BioResource DAC
Data Access Committee EGAC00001000259
EGAC00001000259 | EGA
UnknownA synopsis of global frontiers in fertility preservation.
Since 2007, the Oncofertility Consortium Annual Conference has brought together a diverse network of individuals from a wide range of backgrounds and professional levels to disseminate emerging basic and clinical research findings in fertility preservation. This network also developed enduring educa...
S-EPMC9307970 | biostudies-literature
UnknownArtesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial.

Background

Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice, although evidence from Asia suggests that artesunate is associated with a lower mortality. We...
S-EPMC3033534 | biostudies-literature
UnknownBioTIME: A database of biodiversity time series for the Anthropocene.

Motivation

The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a c...
S-EPMC6099392 | biostudies-literature
UnknownThe African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa.

Background

Critical illness represents a major global health-care burden and critical care is an essential component of hospital care. There are few data describing the prevalence, treatment, and outcomes of critically ill patients in African hospitals.

Methods

This was an internation...
S-EPMC11872788 | biostudies-literature
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