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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
ProteomicsNovel Conformation Specific Inhibitors of Activated GTPases reveal Ras-dependency of Patient-Derived Cancer Organoids
The small GTPases H, K, and NRAS are molecular switches that are indispensable for proper regulation of cellular proliferation and growth. Mutations in this family of proteins are associated with cancer and result in aberrant activation of signaling processes caused by a deregulated recruitment of d...
ORGANISM(S): Homo sapiens (Human) 
2020-03-05 | PXD016827 | Pride
Ip-ms Protein-engineering Ras-binding domain 
UnknownIntersession Experience Questionnaire Short (IEQ-S): psychometric properties and longitudinal associations with symptoms of an 8-item short version of the Intersession Experience Questionnaire.
Not available
S-EPMC12685439 | biostudies-literature
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