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ProteomicsComprehensive proteomic analysis of human erythropoiesis - experiment1
We performed a proteomic analysis of human erythropoiesis using 4 umbilical cord's blood samples. This study revealed the absolute and quantitative expression of more than 6000 proteins throughout 7 stages of erythroid differentiation using a label-free technique. We found new informations on erythr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-17 | MSV000080060 | MassIVE
MetabolomicsAssociation of hemodialysis patient plasma trace metals with response to erythropoiesis stimulating agents
Not available
ORGANISM(S): Homo sapiens 
ST000565 | MetabolomicsWorkbench
ProteomicsComprehensive proteomic analysis of human erythropoiesis - experiment 2
We performed a proteomic analysis of human erythropoiesis using 4 umbilical cord's blood samples. This study revealed the absolute and quantitative expression of more than 6000 proteins throughout 7 stages of erythroid differentiation using a label-free technique. We found new informations on erythr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-17 | MSV000080061 | MassIVE
ProteomicsComprehensive proteomic analysis of human erythropoiesis - experiment 3 over 4
We performed a proteomic analysis of human erythropoiesis using 4 umbilical cord's blood samples. This study revealed the absolute and quantitative expression of more than 6000 proteins throughout 7 stages of erythroid differentiation using a label-free technique. We found new informations on erythr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-17 | MSV000080063 | MassIVE
ProteomicsComprehensive proteomic analysis of human erythropoiesis - experiment 4 over 4
We performed a proteomic analysis of human erythropoiesis using 4 umbilical cord's blood samples. This study revealed the absolute and quantitative expression of more than 6000 proteins throughout 7 stages of erythroid differentiation using a label-free technique. We found new informations on erythr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-17 | MSV000080059 | MassIVE
TranscriptomicsRNA-seq expression profiles during terminal erythropoiesis
It is unclear how epigenetic changes regulate the induction of erythroid-specific genes during terminal erythropoiesis. Here we use global mRNA sequencing (mRNA-seq) and chromatin immunoprecipitation coupled to high-throughput sequencing (CHIP-seq) to investigate the changes that occur in mRNA level...
ORGANISM(S): Mus musculus 
2011-09-13 | E-GEOD-32110 | biostudies-arrayexpress
ProteomicsBRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK
Erythropoiesis is a crucial part in hematopoietic system, while facing disruptions from various diseases conditions. Anemia and blood shortages has become global challenges, with current finite pharmacological options like EPO or glucocorticoids having limitations, especially in genetic anemias like...
ORGANISM(S): Homo Sapiens 
2024-09-09 | PXD055730 |
GenomicsComparative profiling of chromatin state maps and transcription factor occupancy during human fetal and adult erythropoiesis
We report the comparative investigation of genome-wide chromatin state maps, transcription factor (TF) occupancy, and gene expression profiles from developing red cell precursors at two developmental stages. Contrasting the similarities and differences between fetal and adult erythropoiesis provides...
ORGANISM(S): Homo sapiens 
2012-10-05 | E-GEOD-36985 | biostudies-arrayexpress
ProteomicsThe proteome and phosphorylproteome of human early erythropoiesis
In order to revealed the multiple protein functional modules and kinases networks of human early erythropoiesis. We isolated the CD34+ cells drived from Human umbilical cord blood samples and induced to undergo erythropoiesis in vitro. Then, the cultured erythroid cells were sorted with FACS and sam...
ORGANISM(S): Homo Sapiens 
2022-08-03 | PXD035785 |
ProteomicsIn vitro erythropoiesis at different pO2 induces adaptations that are independent of prior systemic exposure to hypoxia
Hypoxia is associated with increased erythropoietin (EPO) release to drive erythropoiesis. However, a prolonged sojourn at high altitude results in an increase in EPO levels followed by a decrease, although erythropoiesis remains elevated at a stable level. The role of hypoxia and related EPO adjust...
ORGANISM(S): Homo sapiens (Human) 
2022-04-06 | PXD031776 | Pride
Human Lumos Erythropoiesis 
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