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MetabolomicsAn Evolutionarily Conserved Metabolite Inhibits Biofilm Formation in Escherichia coli K-12
Methylerythritol cyclodiphosphate (MEcPP) is an intermediate in the biosynthesis of isoprenoids in plant plastids and in bacteria, and acts as a stress signal in plants. Here, we show that MEcPP regulates biofilm formation in Escherichia coli K-12 MG1655. Increased MEcPP levels, triggered by genetic...
2024-11-01 | MTBLS2240 | MetaboLights
MetabolomicsMetabolomics characterized concentration-dependent metabolic influence of magnesium on biofilm formation in Escherichia coli (Part 2)
Not available
ORGANISM(S): Escherichia coli 
ST001939 | MetabolomicsWorkbench
MetabolomicsMetabolomics characterized concentration-dependent metabolic influence of magnesium on biofilm formation in Escherichia coli (Part1)
Not available
ORGANISM(S): Escherichia coli 
ST001938 | MetabolomicsWorkbench
TranscriptomicsE coli MG1655 biofilm and planktonic gene expression
Bacteria growing as surface-adherent biofilms are better able to withstand chemical and physical stresses than their unattached, planktonic counterparts. Using transcriptional profiling and quantitative PCR, we observed a previously uncharacterized gene, yjfO, to be upregulated during Escherichia co...
ORGANISM(S): Escherichia coli 
2010-06-21 | E-GEOD-18362 | biostudies-arrayexpress
TranscriptomicsE. coli BW25113 ompA mutant vs wild type biofilm and E. coli BW25113 ompA/pCA24N_ompA vs ompA/pCA24N suspension cells
This Series involves two studies: 1) The gene expression of E. coli K-12 BW25113 ompA mutant strain vs. wild type strain glasswool biofilm cells and E. coli K-12 BW25113 ompA mutant vs. wild type polystyrene biofilm cells. 2) The gene expression of E. coli BW25113 ompA/pCA24N_ompA vs. ompA/pCA24N su...
ORGANISM(S): Escherichia coli 
2010-11-03 | E-GEOD-14064 | biostudies-arrayexpress
TranscriptomicsGene expression of E. coli MG1655 at attachment, colony formation and maturation during biofilm formation
Gene expression changes during biofilm formation processes were investigated. The gene expression was compared at attachment, colony formation and maturation during biofilm formation. At the same time, the gene expressions were also compared with exponential phase and stationary phase in planktonic ...
ORGANISM(S): Escherichia coli 
2009-04-01 | E-GEOD-13418 | biostudies-arrayexpress
GenomicsBolA is a transcriptional switch that turns off motility and turns on biofilm development (ChIP-seq)
Bacteria are extremely versatile organisms which rapidly adapt to changing environments. When Escherichia coli cells switch from planktonic growth to biofilm, flagellum formation is turned off, and the production of fimbriae and extracellular polysaccharides is switched on. Here we show that BolA pr...
ORGANISM(S): Escherichia coli 
2015-02-19 | E-GEOD-58623 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli K-12 mutant ycfR biofilm vs wild type 15 hr LB glu biofilm cells
E. coli K-12 BW25113 mutant strain ycfR expression in biofilm cells relative to E. coli wild-type strain expression in biofilm cells. All samples cultured in LB glu with glass wool Experiment Overall Design: Strains: E. coli K-12 BW25113 wild type and mutant ycfR Experiment Overall Design: Medium: ...
ORGANISM(S): Escherichia coli 
2008-06-14 | E-GEOD-5904 | biostudies-arrayexpress
MetabolomicsIntegrating two chromatographies in a co-fractionation mass spectrometry approach improved protein-metabolite interactions (PMIs) mapping capabilities and revealed novel protein-ligand pairings in Escherichia coli.
The protein-metabolite interactome remains understudied. We previously developed a co-fractionation mass-spectrometry-based approach called PROMIS to address this gap. PROMIS relies on size separation chromatography of protein-metabolite complexes from lysates, followed by proteomics and metabolomic...
2025-04-25 | MTBLS9098 | MetaboLights
no omics definedTranscription profiling of two E. coli ABU strains during biofilm growth in human urine
Gene expression profiling of two different E. coli ABU strains during biofilm growth in human urine.
ORGANISM(S): Escherichia coli 
2007-02-02 | E-MEXP-926 | biostudies-arrayexpress
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