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ProteomicsAdaptation of CysPAT technique to characterize endogenous S-nitrosylation in RAW264.7 cells
The aim of the study was to adapt the CysPAT technique to efficiently identify and characterize endogenous S-nitrosylation in cells under physiological conditions of an experiment from a small amount of sample. Using a macrophage cell line RAW 264.7 we compared the efficacy of the method in the iden...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-22 | PXD008182 | Pride
Post-translational modifications (ptms) Immune system S-nitrosylation Proteomics Macrophages 
ProteomicsOleuropein reprograms the immunosuppressive footprint of tumor-associated myeloid cells and enhances PD-L1/PD-1 blockade immunotherapy in cancer
Therapies based on PD-1/PD-L1 blockade fail in most cancer patients. Here we evaluated the capacities of oleuropein to reprogram tumor-associated immunosuppressive myeloid cells to increase the potency of immunotherapies. Oleuropein caused major global reprogramming of monocytic and granulocytic mye...
ORGANISM(S): Homo Sapiens (human) 
2024-12-08 | PXD047616 | JPOST Repository
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