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TranscriptomicsChIP for H3K27me3 in Murine ES Cells: wild type and Ring1B-/- cells
Native ChIP on chip for H3K27me3 in murine ES cells comparing WT and Ring1B-/- cells. Paper Abstract: How polycomb group proteins repress gene expression in vivo is not known. Whilst histone modifying activities of the polycomb repressive complexes have been studied extensively, in vitro data has su...
ORGANISM(S): Mus musculus 
2010-05-14 | E-GEOD-20213 | biostudies-arrayexpress
TranscriptomicsMurine Embryonic Stems Cells: H3K27me3 in Undifferentiated (UD) and Day 3 (D3) differentiated ES cells
ChIP on chip for H3K27me3 in murine ES cells comparing Undifferentiated and Day 3 differentiated. Paper Abstract: How polycomb group proteins repress gene expression in vivo is not known. Whilst histone modifying activities of the polycomb repressive complexes have been studied extensively, in vitro...
ORGANISM(S): Mus musculus 
2010-05-14 | E-GEOD-20201 | biostudies-arrayexpress
TranscriptomicsChip-chip from WT and Polycomb Component Kock Out Mouse ES cells for H2AZ, H3K27me3, EZH2 and Ring1B.
The essential histone variant H2A.Z localises to both active and silent chromatin sites. In embryonic stem cells (ESCs), H2A.Z is also reported to co-localise with polycomb repressive complex 2 (PRC2) at developmentally silenced genes. The mechanism of H2A.Z targeting is not clear, but a role for th...
ORGANISM(S): Mus musculus 
2012-04-15 | E-GEOD-36999 | biostudies-arrayexpress
TranscriptomicsGain and loss of H4K16 acetylation during ES cell differentiation [Agilent arrays]
Genome wide gain and loss of H4K16ac upon differentiation correlated with changes in expression. Gene expression in undifferentiated ES cells, and cells after 3 days of differentiation in retinoic acid. 3 biological replicates with two technical replicates were performed for each sample.
ORGANISM(S): Mus musculus 
2013-08-23 | E-GEOD-43101 | biostudies-arrayexpress
TranscriptomicsProfile of H4K16 acetylation in undifferentiated ES cells [Illumina BeadArray data]
Level of H4K16ac on highest and lowest expressed genes in undifferentiated ES cells 3 biological replicates in undifferentiated ES cells
ORGANISM(S): Mus musculus 
2013-08-23 | E-GEOD-43100 | biostudies-arrayexpress
TranscriptomicsEffect of c-Myb knockdown on global gene expression
Effect of c-Myb knockdown in K562 on global gene expression after knockdown using siRNA oligo si323 or si2992.
ORGANISM(S): Homo sapiens 
2012-01-01 | E-MTAB-807 | biostudies-arrayexpress
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