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Transcriptomicsgene expression profiles of Barrett's esophagus, squamous esophagus and gastric cardia
SAGE performed on biopsies of Barrett's esophagus, squamous esophagus and gastric cardia taken from a metaplastic Barrett's esophagus patient. Keywords: SAGE comparative analysis of gene expression profiles of Barrett's esophagus, normal squamous esophagus and gastric cardia tissue
ORGANISM(S): Homo sapiens 
2005-06-20 | E-GEOD-2769 | biostudies-arrayexpress
TranscriptomicsWhole transcriptome profiling of Esophageal adenocarcinoma and Barrett's
RNA-seq was performed on esophageal adenocarcinoma (EAC), Barrett's without dysplasia, Barrett's with low-grade dysplasia (LGD) and normal squamous esophagus tissue to find early alterations in the transcriptome level turning Barrett's dysplastic.
ORGANISM(S): Homo sapiens 
2017-07-23 | E-MTAB-4054 | biostudies-arrayexpress
TranscriptomicsWhole genome expression array profiling highlights differences in mucosal defense genes in Barrett's esophagus and esophageal adenocarcinoma.
Esophageal adenocarcinoma (EAC) has become a major concern in Western countries due to rapid rises in incidence coupled with very poor survival rates. One of the key risk factors for the development of this cancer is the presence of Barrett’s esophagus (BE), which is believed to form in response to ...
ORGANISM(S): Homo sapiens 
2011-08-16 | E-GEOD-28302 | biostudies-arrayexpress
TranscriptomicsProcessed small RNA sequencing data of healthy and disease tissue samples from patients with esophageal adenocarcinoma or precursor lesions
In the past decades, the incidence of esophageal adenocarcinoma has increased dramatically in Western populations. Better understanding of disease etiology along with the identification of novel prognostic and predictive biomarkers are urgently needed to improve the dismal survival probabilities. He...
ORGANISM(S): Homo sapiens 
2022-01-01 | E-MTAB-10003 | biostudies-arrayexpress
TranscriptomicsBarrett's esophagus
Barrett's esophagus transcriptome was analysed and compared with Barrett's esophagus primary cell culture and esophageal adenocarcinoma. Keywords: SAGE analysis to compare tissues Barrett's esophagus biopsy was taken from 1 male metaplastic Barrett's esophagus patient. Barrett's esophagus primary ce...
ORGANISM(S): Homo sapiens 
2006-06-28 | E-GEOD-5155 | biostudies-arrayexpress
TranscriptomicsOverall aiEMT in non-cancerous samples of esophageal cancer patients
Surgical samples have long been used as important subjects for cancer research. In accordance with an increase of neoadjuvant therapy, biopsy samples have recently become imperative for cancer transcriptome. On the other hand, both biopsy and surgical samples are available for expression profiling f...
ORGANISM(S): Homo sapiens 
2011-10-06 | E-GEOD-32700 | biostudies-arrayexpress
TranscriptomicsOverall aiEMT in surgical samples of esophageal cancer patients
Surgical samples have long been used as important subjects for cancer research. In accordance with an increase of neoadjuvant therapy, biopsy samples have recently become imperative for cancer transcriptome. On the other hand, both biopsy and surgical samples are available for expression profiling f...
ORGANISM(S): Homo sapiens 
2011-10-19 | E-GEOD-33103 | biostudies-arrayexpress
TranscriptomicsIndividual aiEMT in surgical samples of esophageal cancer patients
Surgical samples have long been used as important subjects for cancer research. In accordance with an increase of neoadjuvant therapy, biopsy samples have recently become imperative for cancer transcriptome. On the other hand, both biopsy and surgical samples are available for expression profiling f...
ORGANISM(S): Homo sapiens 
2011-10-06 | E-GEOD-32701 | biostudies-arrayexpress
ProteomicsGlobal Phospho-Proteomic Profiling of Pathway-Level Molecular Alterations in Barrett’s Esophagus
In the present study, we applied deep, quantitative mass-spectrometry to clinical samples (Barrett’s esophagus and matched adjacent normal biopsies) to gain a mechanistic understanding of the molecular pathways associated with disease progression. From our rich LC/MS profiles, we identified a robust...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD023293 | Pride
Biopsy  systems biology  mass spectrometry  disease signature 
TranscriptomicsCopy number variation analysis of human Barrett's esophagus stem cells (HumanOmniZhongHua-8 v1.1 Beadchip)
Barrett’s esophagus confers significant risk of esophageal adenocarcinoma. We have established the cloning system of patient-matched stem cells of Barrett’s esophagus and gastric cardia. Barrett's esophagus (BE) stem cells and gastric cardia (GC) stem cells from 12 patients were cloned. To ana...
ORGANISM(S): Homo sapiens 
2016-01-13 | E-GEOD-68663 | biostudies-arrayexpress
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